Evidence map›Paper›PMID 33939192›Full record

ArticleBritish journal of clinical pharmacology2021

Good Clinical Trials by removing defensive interpretation of Good Clinical Practice guidelines.

Jonas M den Heijer, Jules A A C Heuberger, Hemme Hijma, Annelieke C Kruithof, Jeroen van Smeden, Geert Jan Groeneveld, Jacobus Burggraaf, Adam Cohen

Abstract read
In one paragraph

Article in British journal of clinical pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jonas M den HeijerClinical Pharmacology, Centre for Human Drug Research, Leiden, The Netherlands.ORCID 0000-0002-2272-7978
Jules A A C HeubergerClinical Pharmacology, Centre for Human Drug Research, Leiden, The Netherlands.
Hemme HijmaClinical Pharmacology, Centre for Human Drug Research, Leiden, The Netherlands.
Annelieke C KruithofClinical Pharmacology, Centre for Human Drug Research, Leiden, The Netherlands.
Jeroen van SmedenClinical Pharmacology, Centre for Human Drug Research, Leiden, The Netherlands.
Geert Jan GroeneveldClinical Pharmacology, Centre for Human Drug Research, Leiden, The Netherlands.
Jacobus BurggraafClinical Pharmacology, Centre for Human Drug Research, Leiden, The Netherlands.
Adam CohenClinical Pharmacology, Centre for Human Drug Research, Leiden, The Netherlands.ORCID 0000-0001-7452-6222

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Practice Patterns, Physicians'Humansbureaucracyclinical trialsdrug developmentregulation

Identifiers

PMID33939192
PMCPMC9292589

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.