Evidence map›Paper›PMID 33938961›Full record

ArticleInternational urogynecology journal2022

Pelvic organ prolapse recurrence after apical prolapse repair: does obesity matter?

Nina Durchfort Metcalfe, Lisa M Shandley, Marisa Rogers Young, Michelle Higgins, Chidimma Abanulo, Gina M Northington

Abstract read
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In one paragraph

Article in International urogynecology journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Nina Durchfort MetcalfeDepartment of Gynecology and Obstetrics, Emory University School of Medicine, Emory Gyn/Ob Clinic, 1365 Clifton Road, Bldg A, 4th Floor, Attention Daphne Blow, Atlanta, GA, 30322, USA. Nina.Metcalfe@emory.edu.ORCID http://orcid.org/0000-0002-9553-5555
Lisa M ShandleyDepartment of Gynecology and Obstetrics, Emory University School of Medicine, Emory Gyn/Ob Clinic, 1365 Clifton Road, Bldg A, 4th Floor, Attention Daphne Blow, Atlanta, GA, 30322, USA.
Marisa Rogers YoungDepartment of Gynecology and Obstetrics, Emory University School of Medicine, Emory Gyn/Ob Clinic, 1365 Clifton Road, Bldg A, 4th Floor, Attention Daphne Blow, Atlanta, GA, 30322, USA.
Michelle HigginsEmory University School of Medicine, Atlanta, GA, USA.
Chidimma AbanuloWomen's Healthcare Associates, Portland, OR, USA.
Gina M NorthingtonDepartment of Gynecology and Obstetrics, Emory University School of Medicine, Emory Gyn/Ob Clinic, 1365 Clifton Road, Bldg A, 4th Floor, Attention Daphne Blow, Atlanta, GA, 30322, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introduction and hypothesisWe hypothesized obesity increases the risk of pelvic organ prolapse recurrence (POP-R) after primary apical prolapse repair.

methodsWe conducted a retrospective cohort study of 353 women who underwent primary apical prolapse surgery from 2011 to 2016. Demographic and clinical data were abstracted from medical records. Multivariable Cox proportional hazard models were used to generate hazard ratios (HR) for association between obesity (BMI ≥ 30 kg/m

resultsTen percent of women developed POP-R. The median follow-up time was 7 months (range 1.4, 63.9). Twenty-four percent of patients were Black and 70% were White; 37% were obese. After controlling for confounders, obese women did not have an increased risk of POP-R (aHR 1.39; 95% CI 0.67, 2.86, p = 0.38). Although only marginally statistically significant, patients who developed POP-R were more likely to be current smokers (aHR 3.48, 95% CI 1.14, 10.67; p = 0.06) or previous smokers (aHR 1.86, 95% CI 0.82, 4.24, p = 0.06) in comparison to non-smokers. Sensitivity analysis showed loss to follow-up had the potential to influence our results.

conclusionsObesity was not a risk factor for POP-R in our cohort. Larger, prospective studies with longer postoperative follow-up time are needed to fully elucidate the relationship between obesity and POP-R.

Indexed as

Pelvic Organ ProlapseCohort StudiesFemaleHumansObesityProspective StudiesRecurrenceRetrospective StudiesTreatment OutcomeApical prolapse repairBody mass indexObesityPelvic organ prolapse recurrence

Identifiers

PMID33938961

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.