Evidence map›Paper›PMID 33938738›Full record

ReviewChemical reviews2021

Molecular Self-Assembly and Supramolecular Chemistry of Cyclic Peptides.

Qiao Song, Zihe Cheng, Maria Kariuki, Stephen C L Hall, Sophie K Hill, Julia Y Rho, Sébastien Perrier

Abstract readReview
In one paragraph

Review in Chemical reviews, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed.

  1. Article
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  10. Review
  11. 2D Assemblies Based on a Tetraphenylethylene D,L-Cyclic Peptide Scaffold.Angewandte Chemie (International ed. in English) · 2025
    Article
  12. Review
  13. Review
  14. Article
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  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Qiao SongDepartment of Chemistry, University of Warwick, Coventry CV4 7AL, U.K.
Zihe ChengDepartment of Chemistry, University of Warwick, Coventry CV4 7AL, U.K.
Maria KariukiDepartment of Chemistry, University of Warwick, Coventry CV4 7AL, U.K.
Stephen C L HallDepartment of Chemistry, University of Warwick, Coventry CV4 7AL, U.K.ORCID 0000-0003-0753-5123
Sophie K HillDepartment of Chemistry, University of Warwick, Coventry CV4 7AL, U.K.
Julia Y RhoDepartment of Chemistry, University of Warwick, Coventry CV4 7AL, U.K.
Sébastien PerrierDepartment of Chemistry, University of Warwick, Coventry CV4 7AL, U.K.ORCID 0000-0001-5055-9046

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This Review focuses on the establishment and development of self-assemblies governed by the supramolecular interactions between cyclic peptides. The Review first describes the type of cyclic peptides able to assemble into tubular structures to form supramolecular cyclic peptide nanotubes. A range of cyclic peptides have been identified to have such properties, including α-peptides, β-peptides, α,γ-peptides, and peptides based on δ- and ε-amino acids. The Review covers the design and functionalization of these cyclic peptides and expands to a recent advance in the design and application of these materials through their conjugation to polymer chains to generate cyclic peptide-polymer conjugates nanostructures. The Review, then, concentrates on the challenges in characterizing these systems and presents an overview of the various analytical and characterization techniques used to date. This overview concludes with a critical survey of the various applications of the nanomaterials obtained from supramolecular cyclic peptide nanotubes, with a focus on biological and medical applications, ranging from ion channels and membrane insertion to antibacterial materials, anticancer drug delivery, gene delivery, and antiviral applications.

Indexed as

NanostructuresNanotubesPeptidesPeptides, CyclicPolymersPeptidesPeptides, CyclicPolymers

Identifiers

PMID33938738
PMCPMC8824434

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.