ArticleNeurogastroenterology and motility2021
Examining the optimal cutoff values of HADS, PHQ-9 and GAD-7 as screening instruments for depression and anxiety in irritable bowel syndrome.
Article in Neurogastroenterology and motility, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 1 of them a synthesis that pooled it.
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Who cites it
46 citing papers in PubMed, 1 synthesis or guideline pooled it, 77 citations in OpenAlex.
- Generalized Anxiety Disorder 7-item (GAD-7) and 2-item (GAD-2) scales for detecting anxiety disorders in adults.The Cochrane database of systematic reviews · 2025Pooled it
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- Improving Nausea Through Breathing Interventions: A Trial of Written Instructions for Diaphragmatic Breathing Versus a Biofeedback Device.Canadian journal of gastroenterology & hepatology · 2026Trial
- The Association Between Personality Traits and Irritable Bowel Syndrome-Insights From an Exploratory Cohort Study.Neurogastroenterology and motility · 2026Observational
- Internet-delivered cognitive behavioral therapy and FODMAP diet for adults with irritable bowel syndrome: A four-arm randomized controlled trial.Internet interventions · 2026Article
- Dietary index for gut microbiota (DI-GM) and irritable bowel syndrome: a case-control study.Scientific reports · 2026Article
- Digital Monitoring of Pre-Exposure Prophylaxis Users Through Electronic Patient-Reported Outcome Measures and Electronic Patient-Reported Experience Measures: Multicenter Prospective Study on Feasibility, Safety, and Predictive Modeling of Digital Engagement.Journal of medical Internet research · 2026Observational
- Effectiveness of alcohol, smoking, and substance involvement screening test (ASSIST)-linked brief intervention in reducing tobacco and alcohol use among coal mine workers: An experience from a randomized controlled trial from West Bengal, India.Indian journal of psychiatry · 2026Article
- Trajectories of Pain Processing in Recurrent Acute and Chronic Pancreatitis: A Longitudinal Quantitative Sensory Testing Study.European journal of pain (London, England) · 2026Observational
- Article
- Effectiveness of a FODMAP-Based, Coach-Supervised, and Peer-Supported Lifestyle Program in Reducing Gastrointestinal and Extraintestinal Symptoms in Irritable Bowel Syndrome.Gastro hep advances · 2026Article
- Poststroke fatigue in subacute and chronic stroke rehabilitation phase: prevalence, associated factors and impact on self-efficacy and functional ability.BMJ neurology open · 2026Article
- Exploratory randomized pilot study of written diaphragmatic breathing instructions vs. a biofeedback device for upper abdominal pain.Open medicine (Warsaw, Poland) · 2026Article
- The panic-sadness bridge: a longitudinal study using undirected and directed network analyses of COVID-19-related anxiety and depression.BMC psychiatry · 2025Article
- Social chronic pain: the affective response to social exclusion.The journal of headache and pain · 2025Article
- Outcome measures for irritable bowel syndrome: a scoping review.BMC medical research methodology · 2025Article
- Multi-omics analysis reveal clinical-gut-brain interactions in female ibs patients with adverse childhood experiences.Biology of sex differences · 2025Article
- Pre-Exercise Factors Associated with the Magnitude of Exercise-Induced Hypoalgesia in Individuals with Knee Osteoarthritis: A Cross-Sectional, Observational Study.Journal of clinical medicine · 2025Article
- Psychological Distress, Post-Traumatic Stress and Emotional Suppression in a Pregnancy After a Perinatal Death: A Longitudinal Survey.BJOG : an international journal of obstetrics and gynaecology · 2025Article
- Drug Addiction in Gay and Bisexual Men Living with HIV Engaged in Sexualized Drug Use: Recent Drug Use, Polydrug and Depressive Symptoms as Predictors.AIDS and behavior · 2025Article
Corrections and comments
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Authors and funding
13 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSelf-rating scales are frequently used to screen for anxiety and depression in patients with irritable bowel syndrome (IBS). Different cutoff values are recommended in literature, and guidelines have suggested the use of other screening instruments over time. The aim of this study was to assess the correlation between the most commonly used psychological screening instruments for anxiety and depression in IBS and to compare custom cutoff scores for these instruments.
methodsIrritable bowel syndrome patients (n = 192) completed several questionnaires including the Hospital Anxiety and Depression Scale (HADS, HADS-A and HADS-D subscale), Patient Health Questionnaire-9 (PHQ-9) and Generalized Anxiety Disorder-7 (GAD-7). Agreement at different cutoff points, for depressive and anxiety disorder, was assessed by use of the Gwet AC1 coefficient. KEY
resultsHospital Anxiety and Depression Scale (HADS)-D and PHQ-9 scores, and HADS-A and GAD-7 scores showed high correlations (r CONCLUSIONS & INFERENCES: Custom cutoff values deem the HADS subscales (HADS-D and HADS-A) concordant to PHQ-9 and GAD-7 scores. The choice of a cutoff value has substantial impact on sensitivity/specificity and is dependent on patient population, setting, and the purpose of use.
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