Evidence map›Paper›PMID 33938161›Full record

ArticleArthritis care & research2022

Costs of Hospital-Associated Care for Patients With Juvenile Idiopathic Arthritis in the Dutch Health Care System.

Michelle M A Kip, Sytze de Roock, Inge van den Berg, Gillian Currie, Deborah A Marshall, Luiza R Grazziotin, Marinka Twilt, Rae S M Yeung, Susanne M Benseler, Sebastiaan J Vastert and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Arthritis care & research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 3 countries.

Michelle M A KipWilhelmina Children's Hospital, Utrecht, The Netherlands, and University of Twente, Enschede, The Netherlands.ORCID 0000-0002-6405-6789
Sytze de RoockWilhelmina Children's Hospital and Utrecht University, Utrecht, The Netherlands.
Inge van den BergUniversity of Twente, Enschede, The Netherlands.
Gillian CurrieUniversity of Calgary, Calgary, Alberta, Canada.ORCID 0000-0002-4681-9893
Deborah A MarshallUniversity of Calgary, Calgary, Alberta, Canada.ORCID 0000-0002-8467-8008
Luiza R GrazziotinUniversity of Calgary, Calgary, Alberta, Canada.
Marinka TwiltUniversity of Calgary, Calgary, Alberta, Canada.
Rae S M YeungUniversity of Toronto, Toronto, Ontario, Canada.
Susanne M BenselerUniversity of Calgary, Calgary, Alberta, Canada.
Sebastiaan J VastertWilhelmina Children's Hospital and Utrecht University, Utrecht, The Netherlands.
Nico WulffraatWilhelmina Children's Hospital and Utrecht University, Utrecht, The Netherlands.
Joost F SwartWilhelmina Children's Hospital and Utrecht University, Utrecht, The Netherlands.
Maarten J IJzermanUniversity of Twente, Enschede, The Netherlands, and University of Melbourne, Melbourne, Australia.
University of Calgary · CAUtrecht University · NLThe University of Melbourne · AUUniversity of Toronto · CAUniversity of Twente · NLWilhelmina Children's Hospital · NL

Funding

CIHR 381280
6 · The paper itself

Abstract

objectiveThe aim of this study was to quantify costs of hospital-associated care for juvenile idiopathic arthritis (JIA), provide insights in patient-level variation in costs, and investigate costs over time from the moment of JIA diagnosis. Results were reported for all JIA patients in general and by subtype. 

methodsThis study was a single-center, retrospective analysis of prospective data from electronic medical records of children with JIA, ages 0-18 years, between April 1, 2011 and March 31, 2019. Patient characteristics (age, sex, JIA subtype) and hospital-based resource use (consultations, medication, radiology procedures, laboratory testing, surgeries, emergency department [ED] visits, hospital stays) were extracted and analyzed. Unit prices were obtained from Dutch reimbursement lists and pharmaceutical and hospital list prices.

resultsThe analysis included 691 patients. The mean total cost of hospital care was €3,784/patient/year, of which €2,103 (55.6%) was attributable to medication. Other costs involved pediatric rheumatologist visits (€633/patient/year [16.7%]), hospital stays (€439/patient/year [11.6%]), other within-hospital specialist visits (€324/patient/year [8.6%]), radiology procedures (€119/patient/year [3.1%]), laboratory tests (€114/patient/year [3.0%]), surgeries (€46/patient/year [1.2%]), and ED visits (€6/patient/year [0.2%]). Mean annual total costs varied between JIA subtypes and between individuals and were the highest for systemic JIA (€7,772/patient/year). Over the treatment course, costs were the highest in the first month after JIA diagnosis.

conclusionHospital care costs of JIA vary substantially between individuals, between subtypes, and over the treatment course. The highest annual costs were for systemic JIA, primarily attributable to medication (i.e., biologics). Costs of other hospital-associated care were comparable regardless of subtype.

Indexed as

Arthritis, JuvenileBiological ProductsAdolescentChildChild, PreschoolHealth Care CostsHospitalsHumansInfantInfant, NewbornPharmaceutical PreparationsProspective StudiesRetrospective StudiesBiological ProductsPharmaceutical Preparations

Identifiers

PMID33938161
PMCPMC9796352
OpenAlexW3158394641

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.