ArticleInternational wound journal2022
Outcomes in patients with chronic leg wounds in Denmark: A nationwide register-based cohort study.
Article in International wound journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 13 citations in OpenAlex.
- Shelf-stable, ready-to-use therapeutic patches: Dip-and-deliver solutions for personalized wound care.Bioengineering & translational medicine · 2026Article
- How Nurses Communicate About Amputation and Death in Specialised Outpatient Wound Clinics-A Qualitative Study.Scandinavian journal of caring sciences · 2026Article
- Epidemiology of first-time major lower extremity amputations- A Danish Nationwide cohort study from 2010 to 2021.European journal of epidemiology · 2025Observational
- Deficient functional wound closure as measured by elevated trans-epidermal water loss predicts chronic wound recurrence: An exploratory observational study.Scientific reports · 2024Observational
- Mortality after major lower extremity amputation and association with index level: a cohort study based on 11,205 first-time amputations from nationwide Danish databases.Acta orthopaedica · 2024Observational
- Wound management, healing, and early prosthetic rehabilitation: Part 2 - A scoping review of physical biomarkers.Canadian prosthetics & orthotics journal · 2024Review
- Individualized Risk Prediction for Improved Chronic Wound Management.Advances in wound care · 2023Review
- Association of vitamin D status with all-cause mortality and outcomes among Chinese individuals with diabetic foot ulcers.Journal of diabetes investigation · 2023Article
- Article
- Outcomes in patients with chronic leg wounds in Denmark: A nationwide register-based cohort study.International wound journal · 2022Article
- Adjunctive Intermittent Vacuum Therapy Is Associated With Faster Healing of Chronic Lower Limb Wounds: A Single-Centre Retrospective Nonrandomised Cohort Study.Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair SocietyArticle
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
This study aimed to investigate incidence and predictors of wound healing, relapse, major amputation, and/or death among patients with chronic leg wounds who were referred to specialist treatment at hospital for their condition. A nationwide register-based cohort study design was applied with 5 years of follow-up. All patients with diagnoses of chronic leg wounds in Denmark between 2007 and 2012 were included (n = 8394). Clinical, social, and demographic individual-level linked data from several Danish national registries were retrieved. Incidence rate per 1000 person-years (PY) was calculated. Predictors were investigated using Cox proportional hazards regression analysis. Incidence rates of having a healed wound was 236 per 1000 PY. For relapse, the incidence rate was 75 per 1000 PY, for amputation 16 per 1000 PY, and for death 100 per 1000 PY. Diabetes, peripheral arteria disease, or other comorbidities were associated with decreased chance of wound healing and increased risk of relapse, major amputation, and death. Regional differences in all four outcomes were detected. Basic or vocational education independently predicted risk of amputation and death. This study provides epidemiological data that may help identify patients at particular risk of poor outcomes. It also elucidates social inequality in outcomes.
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Registered trials
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