Evidence map›Paper›PMID 33938031›Full record

ArticleJournal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine2022

Doppler-Guided Acoustically Active Injection Catheter: Transendocardial Delivery Assessed by an Efficacy Testing Animal Model.

Minako Katayama, Naomi M Gades, Vijay P Singh, Katrina L Devick, David Zarbatany, Veronica V Vaitkus, David L Belohlavek, F David Fortuin, Marek Belohlavek

Open access · greenAbstract read
In one paragraph

Article in Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 96% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Minako KatayamaDepartment of Cardiovascular Diseases, Mayo Clinic, Scottsdale, Arizona, USA.ORCID https://orcid.org/0000-0002-7174-2736
Naomi M GadesDepartment of Comparative Medicine, Mayo Clinic, Scottsdale, Arizona, USA.
Vijay P SinghDepartment of Medicine, Mayo Clinic, Scottsdale, Arizona, USA.
Katrina L DevickDepartment of Quantitative Health Sciences, Mayo Clinic, Scottsdale, Arizona, USA.
David ZarbatanyIndependent Engineering Consultant, Laguna Niguel, California, USA.
Veronica V VaitkusDepartment of Cardiovascular Diseases, Mayo Clinic, Scottsdale, Arizona, USA.
David L BelohlavekDepartment of Cardiovascular Diseases, Mayo Clinic, Scottsdale, Arizona, USA.
F David FortuinDepartment of Cardiovascular Diseases, Mayo Clinic, Scottsdale, Arizona, USA.
Marek BelohlavekDepartment of Cardiovascular Diseases, Mayo Clinic, Scottsdale, Arizona, USA.ORCID https://orcid.org/0000-0002-8424-6715
Mayo Clinic in Arizona · USLaguna Research · US

Funding

Acoustically Active Catheter for Ultrasound-Guided Intramyocardial InjectionsR01EB019947 · NIBIB · MAYO CLINIC ARIZONA · PI BELOHLAVEK, MAREK, FATEMI, MOSTAFA · 2015 to 2018
$1.5M
Mayo Clinic Center for Biomedical Discovery FP00110922NIBIB NIH HHS R01 EB019947NIH HHS R01 EB019947
6 · The paper itself

Abstract

Percutaneous transendocardial injections of therapeutic agents into the myocardium may not always be effective. We used an animal model for assessing the efficacy of the injections using linoleic acid as a testing agent. Efficacious delivery into the myocardium of a beating heart was indicated by rapidly developed local myocardial necrosis and wall motion abnormalities using echocardiography. We employed this experimental model to test our innovative technology, an acoustically active injection catheter. The Doppler ultrasound-guided acoustically active injection catheter effectively delivers the substance to the myocardium but needs further technical improvements to minimize an unwanted systemic distribution of the agent.

Indexed as

Cardiac CatheterizationCathetersAnimalsDisease Models, AnimalInjectionsUltrasonography, Doppleracoustic cathetercolor flow Dopplerexperimental modelimage guidanceultrasound

Identifiers

PMID33938031
PMCPMC11585318
OpenAlexW3158938077

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.