ArticleThe British journal of dermatology2021
Development of a condition-specific patient-reported outcome measure for measuring symptoms and appearance in vascular malformations: the OVAMA questionnaire.
Article in The British journal of dermatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- Effectiveness and Safety of Bleomycin Electrosclerotherapy for Slow-Flow Vascular Malformations: A Systematic Review.Cardiovascular and interventional radiology · 2026Pooled it
- Prevalence and clinical factors that are associated with low health-related quality of life in children with vascular malformations: a cross-sectional study.Annals of medicine and surgery (2012) · 2026Article
- Review
- Patient-Reported Outcomes and Psychosocial Impact of Vascular Malformations in Asian Patients.Journal of clinical medicine · 2025Article
- Targeted medical therapies for vascular anomalies.Hematology. American Society of Hematology. Education Program · 2024Review
- Venous Malformations: Diagnosis, Management, and Future Directions.Seminars in interventional radiology · 2024Review
- Congenital Vascular Malformations in Children: From Historical Perspective to a Multidisciplinary Approach in the Modern Era-A Comprehensive Review.Children (Basel, Switzerland) · 2024Review
- Health-related quality of life in children with congenital vascular malformations.European journal of pediatrics · 2023Article
- Review
- Magnitude and relevance of change in health-related quality of life in patients with vascular malformations treated with sirolimus.Frontiers in medicine · 2023Article
- Surgical management of auricular arteriovenous malformations: A literature review.Laryngoscope investigative otolaryngology · 2022Review
- Targeted treatment of vascular anomalies.International journal of women's dermatology · 2021Review
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe symptoms and appearance of vascular malformations can severely harm a patient's quality of life. The aim of treatment of vascular malformations generally is to improve condition-specific symptoms and/or appearance. Therefore, it is highly important to start testing treatment effects in clinical studies from the patient's perspective.
objectivesTo develop a patient-reported outcome measure for measuring symptoms and appearance in patients with vascular malformations.
methodsA first draft of the patient-reported outcome measure was based on the previously internationally developed core outcome set. The qualitative part of this study involved interviews with 14 patients, which led to a second draft. The second draft was field tested cross-sectionally, after which groups of items were evaluated for adequate internal consistency (Cronbach's alpha > 0·7) to form composite scores. Construct validity was evaluated by testing 13 predefined hypotheses on known-group differences.
resultsThe patient interviews ensured adequate content validity and resulted in a general symptom scale with six items, a head and neck symptom scale with eight items, and an appearance scale with nine items. Cronbach's alpha was adequate for two composite scores: a general symptom score (0·88) and an appearance score (0·85). Ten out of 13 hypotheses on known-group differences were confirmed, confirming adequate construct validity.
conclusionsWith the development of the OVAMA questionnaire, outcomes of patients with vascular malformations can now be evaluated from the patient's perspective. This may help improve the development of evidence-based treatments and the overall care for patients with vascular malformations.
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