Evidence map›Paper›PMID 33937857›Full record

ArticleRadiology. Artificial intelligence2021

Deep Learning to Quantify Pulmonary Edema in Chest Radiographs.

Steven Horng, Ruizhi Liao, Xin Wang, Sandeep Dalal, Polina Golland, Seth J Berkowitz

Abstract read
In one paragraph

Article in Radiology. Artificial intelligence, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
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  5. Role of artificial intelligence in critical care nutrition support and research.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2024
    Review
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  7. Article
  8. Automatic Quantification of COVID-19 Pulmonary Edema by Self-supervised Contrastive Learning.Medical image learning with limited and noisy data : second international workshop, MILLanD 2023, held in conjunction with MICCAI 2023, Vancouver, BC, Canada, October 8, 2023, proceedings. MILLanD (Workshop) : (2nd : 2023 : Vancouver, B... · 2023
    Article
  9. Article
  10. Review
  11. Review
  12. Artificial Intelligence Techniques to Predict the Airway Disorders Illness: A Systematic Review.Archives of computational methods in engineering : state of the art reviews · 2023
    Review
  13. Article
  14. Artificial Intelligence in Critical Care Medicine.Critical care (London, England) · 2022
    Review
  15. Article
  16. Quantifying Pulmonary Edema on Chest Radiographs.Radiology. Artificial intelligence · 2021
    Article
  17. Joint Modeling of Chest Radiographs and Radiology Reports for Pulmonary Edema Assessment.Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention · 2020
    Article
  18. Multimodal Representation Learning via Maximization of Local Mutual Information.Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention
    Article
  19. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Steven HorngDepartment of Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Ave, Boston, MA 02215 (S.H., S.J.B.); Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, Mass (R.L., P.G.); and Clinical Informatics Solutions and Services, Philips Research, Cambridge, Mass (X.W., S.D.).ORCID 0000-0002-0958-1820
Ruizhi LiaoDepartment of Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Ave, Boston, MA 02215 (S.H., S.J.B.); Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, Mass (R.L., P.G.); and Clinical Informatics Solutions and Services, Philips Research, Cambridge, Mass (X.W., S.D.).ORCID 0000-0001-6761-921X
Xin WangDepartment of Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Ave, Boston, MA 02215 (S.H., S.J.B.); Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, Mass (R.L., P.G.); and Clinical Informatics Solutions and Services, Philips Research, Cambridge, Mass (X.W., S.D.).
Sandeep DalalDepartment of Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Ave, Boston, MA 02215 (S.H., S.J.B.); Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, Mass (R.L., P.G.); and Clinical Informatics Solutions and Services, Philips Research, Cambridge, Mass (X.W., S.D.).ORCID 0000-0003-4785-2553
Polina GollandDepartment of Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Ave, Boston, MA 02215 (S.H., S.J.B.); Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, Mass (R.L., P.G.); and Clinical Informatics Solutions and Services, Philips Research, Cambridge, Mass (X.W., S.D.).
Seth J BerkowitzDepartment of Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Ave, Boston, MA 02215 (S.H., S.J.B.); Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, Mass (R.L., P.G.); and Clinical Informatics Solutions and Services, Philips Research, Cambridge, Mass (X.W., S.D.).

Funding

Training and DisseminationP41EB015902 · NIBIB · BRIGHAM AND WOMEN'S HOSPITAL · PI KIKINIS, RON, WESTIN, CARL-FREDRIK · 2012 to 2022
$20.9M
NIBIB NIH HHS P41 EB015902
6 · The paper itself

Abstract

purposeTo develop a machine learning model to classify the severity grades of pulmonary edema on chest radiographs. MATERIALS AND

methodsIn this retrospective study, 369 071 chest radiographs and associated radiology reports from 64 581 patients (mean age, 51.71 years; 54.51% women) from the MIMIC-CXR chest radiograph dataset were included. This dataset was split into patients with and without congestive heart failure (CHF). Pulmonary edema severity labels from the associated radiology reports were extracted from patients with CHF as four different ordinal levels: 0, no edema; 1, vascular congestion; 2, interstitial edema; and 3, alveolar edema. Deep learning models were developed using two approaches: a semisupervised model using a variational autoencoder and a pretrained supervised learning model using a dense neural network. Receiver operating characteristic curve analysis was performed on both models.

resultsThe area under the receiver operating characteristic curve (AUC) for differentiating alveolar edema from no edema was 0.99 for the semisupervised model and 0.87 for the pretrained models. Performance of the algorithm was inversely related to the difficulty in categorizing milder states of pulmonary edema (shown as AUCs for semisupervised model and pretrained model, respectively): 2 versus 0, 0.88 and 0.81; 1 versus 0, 0.79 and 0.66; 3 versus 1, 0.93 and 0.82; 2 versus 1, 0.69 and 0.73; and 3 versus 2, 0.88 and 0.63.

conclusionDeep learning models were trained on a large chest radiograph dataset and could grade the severity of pulmonary edema on chest radiographs with high performance.

Identifiers

PMID33937857
PMCPMC8043362

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.