Evidence map›Paper›PMID 33937769›Full record

ArticleBrain communications2021

Time-dependent diffusion MRI probes cerebellar microstructural alterations in a mouse model of Down syndrome.

Dan Wu, Yi Zhang, Bei Cheng, Susumu Mori, Roger H Reeves, Feng J Gao

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Brain communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Dan WuKey Laboratory for Biomedical Engineering of Ministry of Education, Department of Biomedical Engineering, College of Biomedical Engineering & Instrument Science, Zhejiang University, Hangzhou, Zhejiang 310027, China.ORCID https://orcid.org/0000-0002-9303-5821
Yi ZhangKey Laboratory for Biomedical Engineering of Ministry of Education, Department of Biomedical Engineering, College of Biomedical Engineering & Instrument Science, Zhejiang University, Hangzhou, Zhejiang 310027, China.
Bei ChengDepartment of Radiology, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA.
Susumu MoriDepartment of Radiology, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA.
Roger H ReevesDepartment of Physiology, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA.
Feng J GaoDepartment of Physiology, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA.ORCID https://orcid.org/0000-0002-5548-5055
Johns Hopkins University · USZhejiang University · CN

Funding

GENOMIC APPROACHES TO ANEUPLOIDYR01HD038384 · NICHD · JOHNS HOPKINS UNIVERSITY · PI REEVES, ROGER H · 2000 to 2020
$11.0M
NICHD NIH HHS R01 HD038384
6 · The paper itself

Abstract

The cerebellum is a complex system with distinct cortical laminar organization. Alterations in cerebellar microstructure are common and associated with many factors such as genetics, cancer and ageing. Diffusion MRI (dMRI) provides a non-invasive tool to map the brain structural organization, and the recently proposed diffusion-time (

Indexed as

cerebellar microstructurediffusion MRIdiffusion-time-dependenceDown syndromeoscillating gradient

Identifiers

PMID33937769
PMCPMC8063586
OpenAlexW3145658586

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.