Evidence map›Paper›PMID 33937720›Full record

ReviewOTA international : the open access journal of orthopaedic trauma2021

Polytrauma: update on basic science and clinical evidence.

Aaron Nauth, Frank Hildebrand, Heather Vallier, Timothy Moore, Luke Leenen, Todd Mckinley, Hans-Christoph Pape

Abstract readReview
In one paragraph

Review in OTA international : the open access journal of orthopaedic trauma, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Beyond the initial impact: a systematic review of post-traumatic bone loss and its mechanisms.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
    Pooled it
  2. Neutrophil phenotyping reflects injury severity when base excess and lactate remain normal.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Polytrauma impairs fracture healing accompanied by increased persistence of innate inflammatory stimuli and reduced adaptive response.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2025
    Article
  8. Review
  9. Is polytrauma really just a simple accident? Recurrent characteristic of polytrauma.Archives of public health = Archives belges de sante publique · 2024
    Article
  10. Article
  11. Review
  12. Article
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Aaron NauthDivision of Orthopaedics, Department of Surgery, University of Toronto and St. Michael's Hospital, Toronto, Ontario, Canada.
Frank HildebrandDepartment of Trauma and Reconstructive Surgery, University Hospital RWTH Aachen. Aachen, Germany.
Heather VallierCase Western Reserve University, The MetroHealth System, Cleveland, OH.
Timothy MooreCase Western Reserve University, The MetroHealth System, Cleveland, OH.
Luke LeenenDepartment of Trauma, UMC Utrecht, Utrecht, The Netherlands.
Todd MckinleyIndiana University School of Medicine, Indianapolis, IN.
Hans-Christoph PapeDepartment of Trauma, University Hospital Zurich, University of Zurich, Zurich, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The management of multiply injured or severely injured patients is a complex and dynamic process. Timely and safe fracture fixation is a critical component of the multidisciplinary care that these patients require. Effective management of these patients, and their orthopaedic injuries, requires a strong understanding of the pathophysiology of the response to trauma and indicators of patient status, as well as an appreciation for the dynamic nature of these parameters. Substantial progress in both clinical and basic science research in this area has advanced our understanding of these concepts and our approach to management of the polytraumatized patient. This article summarizes a symposium on this topic that was presented by an international panel of experts at the 2020 Virtual Annual Meeting of the Orthopaedic Trauma Association.

Indexed as

damage control surgeryearly appropriate careinflammationneutrophilpolytrauma

Identifiers

PMID33937720
PMCPMC8016602

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.