Evidence map›Paper›PMID 33937589›Full record

ArticleBioactive materials2021

Covalent functionalization of decellularized tissues accelerates endothelialization.

Eleonora Dal Sasso, Annj Zamuner, Andrea Filippi, Filippo Romanato, Tiziana Palmosi, Luca Vedovelli, Dario Gregori, José Luís Gómez Ribelles, Teresa Russo, Antonio Gloria and 3 more

Open access · goldAbstract read
In one paragraph

Article in Bioactive materials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Eleonora Dal SassoDepartment of Cardiac, Thoracic and Vascular Sciences and Venetian Institute of Molecular Medicine, Padua, Italy.
Annj ZamunerDepartment of Industrial Engineering, University of Padua, Padua, Italy.
Andrea FilippiLIFELAB Program, Consorzio per la Ricerca Sanitaria, CORIS, Veneto Region, Italy.
Filippo RomanatoLIFELAB Program, Consorzio per la Ricerca Sanitaria, CORIS, Veneto Region, Italy.
Tiziana PalmosiDepartment of Cardiac, Thoracic and Vascular Sciences and Venetian Institute of Molecular Medicine, Padua, Italy.
Luca VedovelliDepartment of Cardiac, Thoracic and Vascular Sciences and Venetian Institute of Molecular Medicine, Padua, Italy.
Dario GregoriDepartment of Cardiac, Thoracic and Vascular Sciences and Venetian Institute of Molecular Medicine, Padua, Italy.
José Luís Gómez RibellesCenter for Biomaterials and Tissue Engineering, CBIT, Universitat Politècnica de València, València, Spain.
Teresa RussoInstitute of Polymers, Composites and Biomaterials, National Research Council of Italy, Naples, Italy.
Antonio GloriaInstitute of Polymers, Composites and Biomaterials, National Research Council of Italy, Naples, Italy.
Laura IopDepartment of Cardiac, Thoracic and Vascular Sciences and Venetian Institute of Molecular Medicine, Padua, Italy.
Gino GerosaDepartment of Cardiac, Thoracic and Vascular Sciences and Venetian Institute of Molecular Medicine, Padua, Italy.
Monica DettinDepartment of Industrial Engineering, University of Padua, Padua, Italy.
Veneto Institute of Molecular Medicine · ITUniversity of Padua · ITNational Research Council · ITBiomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the field of tissue regeneration, the lack of a stable endothelial lining may affect the hemocompatibility of both synthetic and biological replacements. These drawbacks might be prevented by specific biomaterial functionalization to induce selective endothelial cell (EC) adhesion. Decellularized bovine pericardia and porcine aortas were selectively functionalized with a REDV tetrapeptide at 10

Indexed as

Covalent functionalizationDecellularized aortaDecellularized pericardiumEndothelializationMechanical analysisREDV

Identifiers

PMID33937589
PMCPMC8065253
OpenAlexW3159678129

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.