ArticleBioactive materials2021
Hyaluronic acid facilitates bone repair effects of calcium phosphate cement by accelerating osteogenic expression.
Article in Bioactive materials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed.
- Autogenous Demineralized Dentin Graft With High Molecular Weight Hyaluronic Acid in Ridge Preservation: Pilot Trial.Clinical implant dentistry and related research · 2025Trial
- Vanadium-Doped Bioactive Glass-Modified GelMA/CMCS/HA Injectable Hydrogel for Osteosarcoma Postoperative Therapy and Bone Regeneration.Materials (Basel, Switzerland) · 2026Article
- Hydrogels for Bone Repair: Construction Strategies and Applications.Smart medicine · 2026Review
- Engineering polyphenol-based osteogenic system for bone and cartilage repair: Transplantation, tissue engineering, and organoid.Journal of advanced research · 2026Review
- Sculpting the Future of Bone: The Evolution of Absorbable Materials in Orthopedics.Advanced materials (Deerfield Beach, Fla.) · 2026Review
- Hierarchical chirality of bone cement drives osteoinduction via integrin dependent signaling to accelerate critical bone defect regeneration.Journal of nanobiotechnology · 2025Article
- Point-of-care bone cement based on natural peptide comonomer protects orthopaedic implants from bacterial challenge.Materials today. Bio · 2025Article
- Injectable HAMA-CPC hydrogels loaded with high-yield 3D bioprinted adipose-derived stem cell small extracellular vesicles for increased bone repair.Journal of nanobiotechnology · 2025Article
- Hyaluronan-Containing Injectable Magnesium-Calcium Phosphate Cements Demonstrated Improved Performance, Cytocompatibility, and Ability to Support Osteogenic Differentiation In Vitro.International journal of molecular sciences · 2025Article
- Biomaterial-based strategies for bone cement: modulating the bone microenvironment and promoting regeneration.Journal of nanobiotechnology · 2025Review
- Arthroscopic-Assisted Injection of Calcium Phosphate to Treat Osteochondral Lesion of the Talus.Arthroscopy techniques · 2025Article
- A self-hygroscopic, rapidly self-gelling polysaccharide-based sponge with robust wet adhesion for non-compressible hemorrhage control and infected wounds healing.Bioactive materials · 2025Article
- Advances in 3D-Printed scaffolds for bone defect repair: material strategies and synergistic functional performance.Frontiers in bioengineering and biotechnology · 2025Review
- Prominent Alveolar Bone Graft Substitute Derived from Silk Fibroin/Hyaluronic Acid/Demineralized Dentin Matrix Hybrid Hydrogel.Biomaterials research · 2025Article
- Strontium/magnesium-doped coralline hydroxyapatite for bone regeneration.Regenerative biomaterials · 2025Article
- A biodegradable magnesium phosphate cement incorporating chitosan and rhBMP-2 designed for bone defect repair.Journal of orthopaedic translation · 2024Article
- Reconstructive surgical therapy of peri-implant defects with ribose cross-linked collagen matrix and crosslinked hyaluronic acid - a prospective case series.Clinical oral investigations · 2024Article
- Polysaccharide-Based Composite Systems in Bone Tissue Engineering: A Review.Materials (Basel, Switzerland) · 2024Review
- Preparation of composite calcium phosphate cement scaffold loaded with Hedysarum polysaccharides and its efficacy in repairing bone defects.Journal of materials science. Materials in medicine · 2024Article
- Performance of 3D printed porous polyetheretherketone composite scaffolds combined with nano-hydroxyapatite/carbon fiber in bone tissue engineering: a biological evaluation.Frontiers in bioengineering and biotechnology · 2024Article
Corrections and comments
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Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Calcium phosphate cements (CPC) are widely anticipated to be an optimum bone repair substitute due to its satisfied biocompatibility and degradability, suitable to be used in minimally invasive treatment of bone defects. However the clinical application of CPC is still not satisfied by its poor cohesiveness and mechanical properties, in particular its osteoinductivity. Hyaluronic acid reinforced calcium phosphate cements (HA/CPC) showed extroadinary potential not only enhancing the compressive strength of the cements but also significantly increasing its osteoinductivity. In our study, the compressive strength of HA/CPC increased significantly when the cement was added 1% hyaluronic acid (denoted as 1-HA/CPC). In the meantime, hyaluronic acid obviously promoted ALP activity, osteogenic related protein and mRNA expression of hBMSCs (human bone marrow mesenchymal stem cells)
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