Evidence map›Paper›PMID 33937429›Full record

ArticleComputing in cardiology2020

Improving Localization of Cardiac Geometry Using ECGI.

Jake A Bergquist, Jaume Coll-Font, Brian Zenger, Lindsay C Rupp, Wilson W Good, Dana H Brooks, Rob S MacLeod

Abstract read
In one paragraph

Article in Computing in cardiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Simultaneous Multi-Heartbeat ECGI Solution with a Time-Varying Forward Model: a Joint Inverse Formulation.Functional imaging and modeling of the heart : ... International Workshop, FIMH ..., proceedings. FIMH (Conference) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jake A BergquistScientific Computing and Imaging Institute, University of Utah, SLC, UT, USA.
Jaume Coll-FontCardiovascular Bioengineering & Imaging (CBM) Lab at the Massachusetts General Hospital, Boston (MA) and Harvard Medical School, Boston, MA, USA.
Brian ZengerScientific Computing and Imaging Institute, University of Utah, SLC, UT, USA.
Lindsay C RuppScientific Computing and Imaging Institute, University of Utah, SLC, UT, USA.
Wilson W GoodScientific Computing and Imaging Institute, University of Utah, SLC, UT, USA.
Dana H BrooksDepartment of Electrical and Computer Engineering, Northeastern University, Boston, MA, USA.
Rob S MacLeodScientific Computing and Imaging Institute, University of Utah, SLC, UT, USA.

Funding

TRD - VisualizationP41GM103545 · NIGMS · UNIVERSITY OF UTAH · PI MACLEOD, ROB S. · 2012 to 2019
$9.7M
Center for Integrative Biomedical Computing Legacy TransitionR24GM136986 · NIGMS · UNIVERSITY OF UTAH · PI JOHNSON, CHRISTOPHER R., MACLEOD, ROB S. · 2020 to 2022
$1.6M
Novel Characterization and Detection Techniques for Acute Myocardial IschemiaF30HL149327 · NHLBI · UNIVERSITY OF UTAH · PI ZENGER, BRIAN · 2020 to 2022
$117k
NHLBI NIH HHS F30 HL149327NIGMS NIH HHS P41 GM103545NIGMS NIH HHS R24 GM136986
6 · The paper itself

Abstract

introductionElectrocardiographic imaging (ECGI) requires a model of the torso, and inaccuracy in the position of the heart is a known source of error. We previously presented a method to localize the heart when body and heart surface potentials are known. The goal of this study is to extend this approach to only use body surface potentials.

methodsWe used an iterative coordinate descent optimization to estimate the positions of the heart for several consecutive heartbeats relying on the assumption that the epicardial potential sequence is the same in each beat. The method was tested with data synthesized using measurements from a isolated-heart, torso-tank preparation. Improvement was evaluated in terms of both heart localization and ECGI accuracy.

resultsThe geometric correction resulted in cardiac geometries closely matching ground truth geometry. ECGI accuracy increased dramatically by all metrics using the corrected geometry. DISCUSSION: Future studies will employ more realistic animal models and then human subjects. Success could impact clinical ECGI by reducing errors from respiratory movement and perhaps decrease imaging requirements, reducing both cost and logistical difficulty of ECGI, widening clinical applicability.

Identifiers

PMID33937429
PMCPMC8082332

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.