Evidence map›Paper›PMID 33937418›Full record

ArticleJournal of immunology research2021

Epitope-Based Chicken-Derived Novel Anti-PAD2 Monoclonal Antibodies Inhibit Citrullination.

Masayoshi Aosasa, Md Saddam Hossain, Tomoko Sakata, Keita Koga, Takanari Shigemitsu, Yuji Shoya, Motonori Yamaguchi, Kenji Saito, Mujo Kim

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of immunology research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Masayoshi AosasaPharma Foods International Co. Ltd., 1-49 Goryo-Ohara, Nishikyo Ku, Kyoto 615-8245, Japan.
Md Saddam HossainPharma Foods International Co. Ltd., 1-49 Goryo-Ohara, Nishikyo Ku, Kyoto 615-8245, Japan.ORCID https://orcid.org/0000-0002-0947-5980
Tomoko SakataPharma Foods International Co. Ltd., 1-49 Goryo-Ohara, Nishikyo Ku, Kyoto 615-8245, Japan.
Keita KogaPharma Foods International Co. Ltd., 1-49 Goryo-Ohara, Nishikyo Ku, Kyoto 615-8245, Japan.
Takanari ShigemitsuPharma Foods International Co. Ltd., 1-49 Goryo-Ohara, Nishikyo Ku, Kyoto 615-8245, Japan.
Yuji ShoyaPharma Foods International Co. Ltd., 1-49 Goryo-Ohara, Nishikyo Ku, Kyoto 615-8245, Japan.
Motonori YamaguchiPharma Foods International Co. Ltd., 1-49 Goryo-Ohara, Nishikyo Ku, Kyoto 615-8245, Japan.
Kenji SaitoPharma Foods International Co. Ltd., 1-49 Goryo-Ohara, Nishikyo Ku, Kyoto 615-8245, Japan.ORCID https://orcid.org/0000-0003-2184-7203
Mujo KimPharma Foods International Co. Ltd., 1-49 Goryo-Ohara, Nishikyo Ku, Kyoto 615-8245, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aberrant upregulation of protein arginine deiminase 2- (PAD2-) catalyzed citrullination is reported in various autoimmune diseases (rheumatoid arthritis and multiple sclerosis) and several cancers. Currently, there are no anti-PAD2 monoclonal antibodies (mAbs) that can inhibit the citrullination reaction. Here, an epitope

Indexed as

AnimalsAntibodies, MonoclonalArthritis, RheumatoidChickensCitrullinationEpitope MappingEpitopesHemocyaninsHumansMultiple SclerosisNeoplasmsPeptide LibraryProtein-Arginine Deiminase Type 2Antibodies, MonoclonalEpitopesHemocyaninskeyhole-limpet hemocyaninPADI2 protein, humanPeptide LibraryProtein-Arginine Deiminase Type 2

Identifiers

PMID33937418
PMCPMC8055403
OpenAlexW3152647430

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.