ArticleBioMed research international2021
Appropriateness and Pattern of Antibiotic Prescription in Pediatric Patients at Adigart General Hospital, Tigray, Ethiopia.
Article in BioMed research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
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Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Inappropriate antibiotic prescribing in Ethiopian hospitals: a systematic review.International journal of clinical pharmacy · 2026Pooled it
- National and regional challenges of antibiotic prescribing patterns in pediatric populations across Africa: a systematic review and meta-analysis.Systematic reviews · 2026Pooled it
- Global Prevalence and Associated Factors of Medication Errors in Hospitalized Pediatric Patients: Systematic Review and Meta-Analysis.JMIR pediatrics and parenting · 2026Review
- Determinants of antibiotic prescription pattern and appropriateness in paediatric care in Ghana: a generalized estimating equation approach.BMJ paediatrics open · 2026Article
- Antibiotic use appropriateness and its determinant factors among pediatric pneumonia patients in selected comprehensive specialized hospitals in Northwest Amhara, 2024: a prospective follow-up study.BMC infectious diseases · 2026Article
- Prescribing patterns of antibiotics according to the WHO access, watch, and reserve (AWaRe) classification in the pediatric outpatient department: A prospective study.Pakistan journal of medical sciences · 2025Article
- Observational
- Pattern and appropriateness of antimicrobial prescription for acute respiratory tract infection in primary healthcare settings in Ethiopia.Antimicrobial resistance and infection control · 2025Article
- Antibiotic Prescribing Patterns of Family Medicine Pediatric Visits: A Pharmacoepidemiological Study.Healthcare (Basel, Switzerland) · 2025Article
- Pediatric Medication Prescribing Across Urgent Care Visits: An Epidemiologic View from a Primary Care Setting in the Kingdom of Saudi Arabia.Medical sciences (Basel, Switzerland) · 2025Article
- Knowledge and practices of healthcare professionals regarding antibiotic use in a district hospital, Southern Mozambique: a cross-sectional study.Scientific reports · 2025Article
- Prevalence of inappropriate antibiotic doses among pediatric patients of inpatient, outpatient, and emergency care units in Bangladesh: A cross-sectional study.PLOS global public health · 2024Article
- Evaluation of Antibiotic Prescribing Pattern and Appropriateness among Hospitalized Pediatric Patients: Findings from a Malaysian Teaching Hospital.Infectious disease reports · 2022Article
- Antibiotic prescribing patterns at children's outpatient departments of primary care institutions in Southwest China.BMC primary care · 2022Article
- Evaluation of Antibiotics Use and its Predictors at Pediatrics Ward of Jimma Medical Center: Hospital Based Prospective Cross-sectional Study.Infection and drug resistance · 2022Article
- Assessing antibiotic utilization among pediatric patients in Gaborone, Botswana.SAGE open medicine · 2022Article
- Antibiotic Prescription Pattern, Appropriateness, and Associated Factors in Patients Admitted to Pediatric Wards of Tibebe Ghion Specialized Hospital, Bahir Dar, North West Ethiopia.Infection and drug resistance · 2022Article
- Morbidity and Drug Prescribing Pattern in Pediatric Outpatient Department of Kankai Nagar Hospital of Eastern Nepal.Sage open pediatricsArticle
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4 authors.
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Abstract
backgroundInappropriate and unnecessary use of antibiotics can increase morbidity, mortality, medical expenses or patient cost, and microbial antibiotic resistance. However, in developing countries like Ethiopia, information regarding appropriateness of antibiotic prescribing pattern to guide improvement strategies is scant.
objectiveThe aim of this study was to assess appropriateness and pattern of antibiotic prescription in pediatric patients at pediatric ward of Adigrat General Hospital.
methodsHospital-based retrospective cross-sectional study was conducted to assess the antibiotic prescribing pattern in pediatric inpatient and outpatient ward of Adigrat General Hospital from December 1, 2018 to April 30, 2019. Data was collected by using structured data collection checklist, and the systematic random sampling technique was employed to enroll the required sample size during the study period. Appropriateness of drug use in pediatrics was evaluated using Ethiopian Standard Treatment guideline and WHO pediatric guideline.
resultA total of 692 pediatric patients' medical charts were reviewed. The median age of patients on antibiotics was 3.26 years (IQR: 2-4). Majority (49.13%) of the patients were hospitalized for 5-9 days. SCAP (195), tonsillitis (114), and cellulitis (99) were most frequently encountered pediatric diseases. Penicillins (37.86%) followed by cephalosporins (31.79%) antibiotics were the most prescribed antibiotics in pediatric wards. This study also showed that ceftriaxone and ceftriaxone+amoxicillin were the most frequently used single and combination antibiotics, respectively. The prescribing practices were not stick to WHO core indicators and standards. Inappropriate prescription of antibiotics was observed in 28.3% of patients. Advanced age of children, children aged between 6 to 10 years (AOR = 3.225; CI = 1.080 - 9.630;
conclusionInappropriate antibiotic prescribing was encountered in 28.3% of children. The rate of generic prescription was not in line with WHO recommendation. Advanced age of children was the independent factor for inappropriate use of antibiotics.
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