Evidence map›Paper›PMID 33937377›Full record

ReviewFrontiers in veterinary science2021

Novel Vaccine Technologies in Veterinary Medicine: A Herald to Human Medicine Vaccines.

Virginia Aida, Vasilis C Pliasas, Peter J Neasham, J Fletcher North, Kirklin L McWhorter, Sheniqua R Glover, Constantinos S Kyriakis

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in veterinary science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed
20.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 121 citations in OpenAlex.

  1. Article
  2. Probiotics as Potential Enhancers of Veterinary Vaccines.Probiotics and antimicrobial proteins · 2026
    Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. Aerosolized mRNA monoclonal antibodies: A new frontier in passive immunization for neonatal foals.Molecular therapy : the journal of the American Society of Gene Therapy · 2025
    Article
  13. Review
  14. Review
  15. InactivatedFrontiers in immunology · 2025
    Article
  16. Review
  17. Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Virginia AidaDepartment of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, AL, United States.
Vasilis C PliasasDepartment of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, AL, United States.
Peter J NeashamDepartment of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, AL, United States.
J Fletcher NorthDepartment of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, AL, United States.
Kirklin L McWhorterDepartment of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, AL, United States.
Sheniqua R GloverDepartment of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, AL, United States.
Constantinos S KyriakisDepartment of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, AL, United States.
University of Georgia · USAuburn University · USEmory University · US

Funding

NIAID NIH HHS HHSN272201400004C
6 · The paper itself

Abstract

The success of inactivated and live-attenuated vaccines has enhanced livestock productivity, promoted food security, and attenuated the morbidity and mortality of several human, animal, and zoonotic diseases. However, these traditional vaccine technologies are not without fault. The efficacy of inactivated vaccines can be suboptimal with particular pathogens and safety concerns arise with live-attenuated vaccines. Additionally, the rate of emerging infectious diseases continues to increase and with that the need to quickly deploy new vaccines. Unfortunately, first generation vaccines are not conducive to such urgencies. Within the last three decades, veterinary medicine has spearheaded the advancement in novel vaccine development to circumvent several of the flaws associated with classical vaccines. These third generation vaccines, including DNA, RNA and recombinant viral-vector vaccines, induce both humoral and cellular immune response, are economically manufactured, safe to use, and can be utilized to differentiate infected from vaccinated animals. The present article offers a review of commercially available novel vaccine technologies currently utilized in companion animal, food animal, and wildlife disease control.

Indexed as

companion animalsdisease control and preventionfood animalsinfectious diseasesnew technology vaccinesveterinary vaccines

Identifiers

PMID33937377
PMCPMC8083957
OpenAlexW3156195018

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.