Evidence map›Paper›PMID 33937336›Full record

ArticleFrontiers in molecular biosciences2021

MicroRNA-653-5p Promotes Gastric Cancer Proliferation and Metastasis by Targeting the SOCS6-STAT3 Pathway.

Zengliang Li, Hao Fan, Wangwang Chen, Jian Xiao, Xiang Ma, Peidong Ni, Zekuan Xu, Li Yang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in molecular biosciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 27 citations in OpenAlex.

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  14. Host miRNAs-microbiota interactions in gastric cancer.Journal of translational medicine · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Zengliang LiDepartment of General Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Hao FanDepartment of General Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Wangwang ChenDepartment of General Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Jian XiaoDepartment of General Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Xiang MaDepartment of General Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Peidong NiDepartment of General Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Zekuan XuDepartment of General Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Li YangDepartment of General Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Jiangsu Province Hospital · CNNanjing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MicroRNAs (miRNAs) are emerging as significant regulators of the tumorigenesis of gastric cancer (GC), and may be effective biomarkers for diagnosis, prognosis, and therapeutic targeting for GC. In this study, miR-653-5p was found to be significantly upregulated in GC tissues, serum, and cell lines and was strongly associated with poor prognosis in patients with GC. Furthermore, miR-653-5p promoted GC cell proliferation and metastasis

Indexed as

cancer prognosisgastric cancerJAK2/STAT3 pathwaymiR-653-5pSOCS6

Identifiers

PMID33937336
PMCPMC8082248
OpenAlexW3155831191

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.