Evidence map›Paper›PMID 33937324›Full record

ReviewFrontiers in molecular biosciences2021

Mitochondrial Chaperones and Proteases in Cardiomyocytes and Heart Failure.

Zee Chen, Lei Huang, Alexandria Tso, Shijia Wang, Xi Fang, Kunfu Ouyang, Zhen Han

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in molecular biosciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
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  3. Review
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  11. Application of 4-D ultrasound-derived regional strain and proteomics analysis inAmerican journal of physiology. Heart and circulatory physiology · 2023
    Article
  12. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Zee ChenDepartment of Cardiovascular Surgery, Peking University Shenzhen Hospital, Shenzhen, China.
Lei HuangDepartment of Cardiovascular Surgery, Peking University Shenzhen Hospital, Shenzhen, China.
Alexandria TsoDepartment of Medicine, School of Medicine, University of California, San Diego, La Jolla, CA, United States.
Shijia WangState Key Laboratory of Chemical Oncogenomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Shenzhen, China.
Xi FangDepartment of Medicine, School of Medicine, University of California, San Diego, La Jolla, CA, United States.
Kunfu OuyangDepartment of Cardiovascular Surgery, Peking University Shenzhen Hospital, Shenzhen, China.
Zhen HanState Key Laboratory of Chemical Oncogenomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Shenzhen, China.
Peking University · CNUniversity of California, San Diego · USPeking University Shenzhen Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Heart failure is one of the leading causes of morbidity and mortality worldwide. In cardiomyocytes, mitochondria are not only essential organelles providing more than 90% of the ATP necessary for contraction, but they also play critical roles in regulating intracellular Ca

Indexed as

cardiomyocyteheart failuremitochondrial chaperonemitochondrial proteasemitochondrial protein degradationmitochondrial protein foldingmitochondrial protein homeostasis

Identifiers

PMID33937324
PMCPMC8082175
OpenAlexW3154063568

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.