Evidence map›Paper›PMID 33937200›Full record

ArticleFrontiers in chemistry2021

Improving the Thermostability and Activity of Transaminase From

Jia-Ren Cao, Fang-Fang Fan, Chang-Jiang Lv, Hong-Peng Wang, Ye Li, Sheng Hu, Wei-Rui Zhao, Hai-Bin Chen, Jun Huang, Le-He Mei

Abstract read
In one paragraph

Article in Frontiers in chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Evolving ω-amine transaminaseApplied and environmental microbiology · 2024
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Engineering Novel (Applied and environmental microbiology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jia-Ren CaoSchool of Biological and Chemical Engineering, Zhejiang University of Science and Technology, Hangzhou, China.
Fang-Fang FanSchool of Biological and Chemical Engineering, Zhejiang University of Science and Technology, Hangzhou, China.
Chang-Jiang LvSchool of Biological and Chemical Engineering, Zhejiang University of Science and Technology, Hangzhou, China.
Hong-Peng WangSchool of Biological and Chemical Engineering, Zhejiang University of Science and Technology, Hangzhou, China.
Ye LiSchool of Biological and Chemical Engineering, Zhejiang University of Science and Technology, Hangzhou, China.
Sheng HuSchool of Biotechnology and Chemical Engineering, NingboTech University, Ningbo, China.
Wei-Rui ZhaoSchool of Biotechnology and Chemical Engineering, NingboTech University, Ningbo, China.
Hai-Bin ChenEnzymaster (Ningbo) Bio-Engineering Co., Ltd., Ningbo, China.
Jun HuangSchool of Biological and Chemical Engineering, Zhejiang University of Science and Technology, Hangzhou, China.
Le-He MeiSchool of Biotechnology and Chemical Engineering, NingboTech University, Ningbo, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transaminases that promote the amination of ketones into amines are an emerging class of biocatalysts for preparing a series of drugs and their intermediates. One of the main limitations of (

Indexed as

amine transaminaseenzyme thermal stability systemmolecular dynamics simulationssite-directed mutagenesisthermostability

Identifiers

PMID33937200
PMCPMC8081293

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.