Evidence map›Paper›PMID 33937168›Full record

ArticleFrontiers in public health

Genomic Analysis and Lineage Identification of SARS-CoV-2 Strains in Migrants Accessing Europe Through the Libyan Route.

Fabio Tramuto, Stefano Reale, Alessandra Lo Presti, Francesco Vitale, Claudio Pulvirenti, Giovanni Rezza, Fabrizio Vitale, Giuseppa Purpari, Carmelo Massimo Maida, Salvatore Zichichi and 3 more

Abstract read
In one paragraph

Article in Frontiers in public health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Fabio TramutoDepartment of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties "G. D'Alessandro", University of Palermo, Palermo, Italy.
Stefano RealeMolecular Biology Area, Zoo-prophilactic Experimental Institute of Sicily "A. Mirri", Palermo, Italy.
Alessandra Lo PrestiDepartment of Infectious Diseases, National Health Institute, Rome, Italy.
Francesco VitaleDepartment of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties "G. D'Alessandro", University of Palermo, Palermo, Italy.
Claudio PulvirentiUffici di sanità marittima, aerea e di frontiera (USMAF) - Servizi Assistenza Sanitaria Naviganti (SASN) Sicily, Ministry of Health, Directorate-General for Health Prevention, Rome, Italy.
Giovanni RezzaDirectorate-General for Health Prevention, Ministry of Health, Rome, Italy.
Fabrizio VitaleMolecular Biology Area, Zoo-prophilactic Experimental Institute of Sicily "A. Mirri", Palermo, Italy.
Giuseppa PurpariVirological Diagnostic Area, Zoo-prophilactic Experimental Institute of Sicily "A. Mirri", Palermo, Italy.
Carmelo Massimo MaidaDepartment of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties "G. D'Alessandro", University of Palermo, Palermo, Italy.
Salvatore ZichichiUffici di sanità marittima, aerea e di frontiera (USMAF) - Servizi Assistenza Sanitaria Naviganti (SASN) Sicily, Ministry of Health, Directorate-General for Health Prevention, Rome, Italy.
Silvia ScibettaMolecular Biology Area, Zoo-prophilactic Experimental Institute of Sicily "A. Mirri", Palermo, Italy.
Walter MazzuccoDepartment of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties "G. D'Alessandro", University of Palermo, Palermo, Italy.
Paola StefanelliDepartment of Infectious Diseases, National Health Institute, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many African countries, representing the origin of the majority of refugees, asylum-seekers, and other migrants, toward regions bordering on the Mediterranean area, are experiencing sustained local transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Sicily is one of the main entry gates of migrants crossing into Europe. We conducted a pilot study, based on the full-genome sequencing of SARS-CoV-2 strains isolated from migrants coming to Sicily by crossing the Mediterranean Sea, with the aim to investigate the viral genome polymorphism and to describe their genetic variations and the phylogenetic relationships. On June 21, a nongovernmental organization vessel rescued 210 migrants crossing the Mediterranean Sea from Libya to Sicily. Of them, 13.4% tested positive for SARS-CoV-2. Eighteen whole genome sequences were obtained to explore viral genetic variability. All but one of the sequences clustered with other viral African strains within the lineage A, whereas only one intermixed among B.1 lineage genomes. Our findings documented that most of the investigated migrants acquired SARS-CoV-2 infection before landing in Sicily. However, SARS-CoV-2 transmission during travel or in overcrowded Libyan immigrant camps and/or illegal transport boats could not be ruled out. SARS-CoV-2 molecular surveillance on migrants arriving in Europe through the Sicilian gate may improve the knowledge of global SARS-CoV-2 transmission dynamic also in light of the emergence of new variants.

Indexed as

COVID-19Transients and MigrantsAfricaEuropeGenomicsHumansLibyaMediterranean SeaPhylogenyPilot ProjectsSARS-CoV-2Sicilyasylum-seekerMediterranean Seamigrantmolecular surveillanceNGSSARS-CoV-2

Identifiers

PMID33937168
PMCPMC8082074

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.