Evidence map›Paper›PMID 33937035›Full record

ArticleFrontiers in oncology2021

Radiomic Analysis to Predict Outcome in Recurrent Glioblastoma Based on Multi-Center MR Imaging From the Prospective DIRECTOR Trial.

Alex Vils, Marta Bogowicz, Stephanie Tanadini-Lang, Diem Vuong, Natalia Saltybaeva, Johannes Kraft, Hans-Georg Wirsching, Dorothee Gramatzki, Wolfgang Wick, Elisabeth Rushing and 4 more

Abstract read
In one paragraph

Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Development of A Radiomic Model forInternational journal of molecular sciences · 2023
    Article
  3. Article
  4. Review
  5. Radiation oncology (London, England) · 2022
    Article
  6. Review
  7. Review
  8. Brain Tumor Imaging: Applications of Artificial Intelligence.Seminars in ultrasound, CT, and MR · 2022
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Alex VilsDepartment of Radiation Oncology, University Hospital Zurich, Zurich, Switzerland.
Marta BogowiczDepartment of Radiation Oncology, University Hospital Zurich, Zurich, Switzerland.
Stephanie Tanadini-LangDepartment of Radiation Oncology, University Hospital Zurich, Zurich, Switzerland.
Diem VuongDepartment of Radiation Oncology, University Hospital Zurich, Zurich, Switzerland.
Natalia SaltybaevaDepartment of Radiation Oncology, University Hospital Zurich, Zurich, Switzerland.
Johannes KraftDepartment of Radiation Oncology, University Hospital Zurich, Zurich, Switzerland.
Hans-Georg WirschingDepartment of Neurology, University Hospital Zurich, Zurich, Switzerland.
Dorothee GramatzkiDepartment of Neurology, University Hospital Zurich, Zurich, Switzerland.
Wolfgang WickNeurology Clinic, University Heidelberg Medical School, Heidelberg, Germany.
Elisabeth RushingDepartment of Neuropathology, University Hospital Zurich, Zurich, Switzerland.
Guido ReifenbergerDepartment of Neuropathology, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
Matthias GuckenbergerDepartment of Radiation Oncology, University Hospital Zurich, Zurich, Switzerland.
Michael WellerDepartment of Neurology, University Hospital Zurich, Zurich, Switzerland.
Nicolaus AndratschkeDepartment of Radiation Oncology, University Hospital Zurich, Zurich, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBased on promising results from radiomic approaches to predict

methodsPre-treatment MR-imaging data of 69 patients enrolled into the DIRECTOR trial in recurrent glioblastoma served as a training cohort, and 49 independent patients formed an external validation cohort. Contrast-enhancing tumor and peritumoral volumes were segmented on MR images. 180 radiomic features were extracted after application of two MR intensity normalization techniques: fixed number of bins and linear rescaling. Radiomic feature selection was performed

resultsWe established and validated a radiomic model to predict

conclusionsA radiomic model for prediction of

Indexed as

DIRECTOR triallinear intensity interpolationMGMT statusradiomicsrecurrent glioblastoma

Identifiers

PMID33937035
PMCPMC8079773

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.