Evidence map›Paper›PMID 33936990›Full record

ArticleQuantitative imaging in medicine and surgery2021

Pericoronary adipose tissue attenuation assessed by dual-layer spectral detector computed tomography is a sensitive imaging marker of high-risk plaques.

Xujiao Chen, Yuxue Dang, Hong Hu, Shaowei Ma, Yue Ma, Kunhua Wang, Ting Liu, Xiaomei Lu, Yang Hou

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Quantitative imaging in medicine and surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Pooled it
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  10. Pericarotid Fat as a Marker of Cerebrovascular Risk.AJNR. American journal of neuroradiology · 2024
    Review
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  19. Evaluation of pericoronary adipose tissue attenuation on CT.The British journal of radiology · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Xujiao ChenRadiology Department, Shengjing Hospital of China Medical University, Shenyang, China.
Yuxue DangRadiology Department, Shengjing Hospital of China Medical University, Shenyang, China.
Hong HuRadiology Department, Shengjing Hospital of China Medical University, Shenyang, China.
Shaowei MaDepartment of Cardiology, Shengjing Hospital of China Medical University, Shenyang, China.
Yue MaRadiology Department, Shengjing Hospital of China Medical University, Shenyang, China.
Kunhua WangRadiology Department, People's Hospital of Liaoning Province, Shenyang, China.
Ting LiuRadiology Department, the First Affiliated Hospital of China Medical University, Shenyang, China.
Xiaomei LuCT Clinical Science, Philips Healthcare, Shenyang, China.
Yang HouRadiology Department, Shengjing Hospital of China Medical University, Shenyang, China.
China Medical University · CNLiaoning Provincial People's Hospital · CNPhilips (China) · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe pericoronary fat attenuation index (FAI) derived from conventional polychromatic computed tomography (CT) can capture the presence of coronary inflammation. However, conventional polychromatic CT has limitations in material component differentiation, and spectral CT could have a better ability to discriminate tissue characteristics. Hence, this study sought to assess pericoronary adipose tissue (PCAT) attenuation using spectral CT and explore its association with atherosclerotic plaque characteristics.

methodsWe enrolled 104 patients with coronary atherosclerosis who met the inclusion criteria and underwent coronary CT angiography with dual-layer spectral detector computed tomography (SDCT). Plaque anatomical characteristics were measured, and the PCAT attenuation was assessed by polychromatic images (CT

resultsPCAT attenuation indicators around high-risk plaques were higher than those around non-high-risk plaques, especially CT

conclusionsPCAT surrounding high-risk plaques showed higher attenuation; a finding that has been associated with coronary artery inflammation. The metrics derived from SDCT, especially CT40

Indexed as

computed tomography attenuation (CT attenuation)Dual-layer spectral detector computed tomography (dual-layer SDCT)high-risk plaquepericoronary adipose tissue (PCAT)

Identifiers

PMID33936990
PMCPMC8047372
OpenAlexW3134266712

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.