Evidence map›Paper›PMID 33936983›Full record

ArticleQuantitative imaging in medicine and surgery2021

Semiquantitative score of breast arterial calcifications on mammography (BAC-SS): intra- and inter-reader reproducibility.

Rubina Manuela Trimboli, Marina Codari, Andrea Cozzi, Caterina Beatrice Monti, Davide Capra, Carolina Nenna, Diana Spinelli, Giovanni Di Leo, Giuseppe Baselli, Francesco Sardanelli

Open access · diamondAbstract read
In one paragraph

Article in Quantitative imaging in medicine and surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Rubina Manuela TrimboliDepartment of Biomedical Sciences for Health, Università degli Studi di Milano, Milan, Italy.
Marina CodariDipartimento di Elettronica, Informazione e Bioingegneria, Politecnico di Milano, Milan, Italy.
Andrea CozziDepartment of Biomedical Sciences for Health, Università degli Studi di Milano, Milan, Italy.
Caterina Beatrice MontiDepartment of Biomedical Sciences for Health, Università degli Studi di Milano, Milan, Italy.
Davide CapraDepartment of Biomedical Sciences for Health, Università degli Studi di Milano, Milan, Italy.
Carolina NennaCorso di Laurea in Medicina e Chirurgia, Università degli Studi di Milano, Milan, Italy.
Diana SpinelliPostgraduation School in Radiodiagnostics, Università degli Studi di Milano, Milan, Italy.
Giovanni Di LeoUnit of Radiology, IRCCS Policlinico San Donato, San Donato Milanese, Italy.
Giuseppe BaselliDipartimento di Elettronica, Informazione e Bioingegneria, Politecnico di Milano, Milan, Italy.
Francesco SardanelliDepartment of Biomedical Sciences for Health, Università degli Studi di Milano, Milan, Italy.
University of Milan · ITPolitecnico di Milano · ITIRCCS Policlinico San Donato · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBreast arterial calcifications (BAC), representing Mönckeberg's sclerosis of the tunica media of breast arteries, are an imaging biomarker for cardiovascular risk stratification in the female population. Our aim was to estimate the intra- and inter-reader reproducibility of a semiquantitative score for BAC assessment (BAC-SS).

methodsConsecutive women who underwent screening mammography at our center from January 1

resultsAmong 408 women, 57 (14%) had BAC; 114 medio-lateral oblique views were assessed. Median BAC score was 4 [interquartile range (IQR): 3-6] for R1 and 4 (IQR: 2-6) for R2 (P=0.417) while median scoring time was 156 s (IQR: 99-314 s) for R1 and 191 s (IQR: 137-292 s) for R2 (P=0.743). Bland-Altman analysis showed a 77% intra-reader reproducibility [bias: 0.193, coefficient of repeatability (CoR): 0.955] and a 64% inter-reader reproducibility (bias: 0.211, CoR: 1.516). Cohen's κ for BAC presence was 0.968 for intra-reader agreement and 0.937 for inter-reader agreement.

conclusionsOur BAC-SS has a good intra- and inter-reader reproducibility, within acceptable scoring times. A large-scale study is warranted to test its ability to stratify cardiovascular risk in women.

Indexed as

biomarkersCardiovascular diseasesmammographyMönckeberg medial calcific sclerosisreproducibility of results

Identifiers

PMID33936983
PMCPMC8047367
OpenAlexW3134713453

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.