Evidence map›Paper›PMID 33936967›Full record

ArticleQuantitative imaging in medicine and surgery2021

Split-filter dual-energy CT pulmonary angiography for the diagnosis of acute pulmonary embolism: a study on image quality and radiation dose.

Bernhard Petritsch, Pauline Pannenbecker, Andreas M Weng, Jan-Peter Grunz, Simon Veldhoen, Thorsten A Bley, Aleksander Kosmala

Open access · diamondAbstract read
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Article in Quantitative imaging in medicine and surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Bernhard PetritschDepartment of Diagnostic and Interventional Radiology, University Hospital Würzburg, Würzburg, Germany.
Pauline PannenbeckerDepartment of Diagnostic and Interventional Radiology, University Hospital Würzburg, Würzburg, Germany.
Andreas M WengDepartment of Diagnostic and Interventional Radiology, University Hospital Würzburg, Würzburg, Germany.
Jan-Peter GrunzDepartment of Diagnostic and Interventional Radiology, University Hospital Würzburg, Würzburg, Germany.
Simon VeldhoenDepartment of Diagnostic and Interventional Radiology, University Hospital Würzburg, Würzburg, Germany.
Thorsten A BleyDepartment of Diagnostic and Interventional Radiology, University Hospital Würzburg, Würzburg, Germany.
Aleksander KosmalaDepartment of Diagnostic and Interventional Radiology, University Hospital Würzburg, Würzburg, Germany.
Universitätsklinikum Würzburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundComputed tomography (CT) pulmonary angiography is the diagnostic reference standard in suspected pulmonary embolism (PE). Favorable results for dual-energy CT (DECT) images have been reported for this condition. Nowadays, dual-energy data acquisition is feasible with different technical options, including a single-source split-filter approach. Therefore, the aim of this retrospective study was to investigate image quality and radiation dose of thoracic split-filter DECT in comparison to conventional single-energy CT in patients with suspected PE.

methodsA total of 110 CT pulmonary angiographies were accomplished either as standard single-energy CT with automatic tube voltage selection (ATVS) (n=58), or as split-filter DECT (n=52). Objective [pulmonary artery CT attenuation, signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR)] and subjective image quality [four-point Likert scale; three readers (R)] were compared among the two study groups. Size-specific dose estimates (SSDE), dose-length-product (DLP) and volume CT dose index (CTDIvol) were assessed for radiation dose analysis.

resultsSplit-filter DECT images yielded 67.7% higher SNR (27.0

conclusionsIn the diagnostic workup of acute PE, the split-filter allows for dual-energy data acquisition from single-source single-layer CT scanners. The existing opportunity to assess pulmonary "perfusion" based on analysis of iodine distribution maps is associated with higher radiation dose in terms of increased SSDE than conventional single-energy CT with ATVS. Moreover, a proportion of up to 3.8% non-diagnostic examinations in the current reference standard test for PE is not negligible.

Indexed as

CT-angiographyDual-energyembolism/thrombosispulmonary arteriesvascular

Identifiers

PMID33936967
PMCPMC8047383
OpenAlexW3135563951

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.