Evidence map›Paper›PMID 33936856›Full record

ArticleWestern Pacific surveillance and response journal : WPSAR

A programme to treat chronic hepatitis B in Kiribati: progress and challenges.

Alice U Lee, Kathy Jackson, Rosemary Tekoaua, Caroline Lee, Margaret Sue Huntley, David C Hilmers

Abstract read
In one paragraph

Article in Western Pacific surveillance and response journal : WPSAR. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. A new hepatitis B elimination strategy for remote populations is needed.The Lancet regional health. Western Pacific · 2024
    Article
  4. Review
  5. Article
  6. Article
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alice U LeeUniversity of Sydney, Concord Repatriation General Hospital, Department of Gastroenterology and Liver Services, Concord, New South Wales 2139, Australia.
Kathy JacksonVictorian Infectious Diseases Reference Laboratory, Royal Melbourne Hospital, The Peter Doherty Institute for Infection and Immunity, Victoria, Australia.
Rosemary TekoauaMinistry of Health and Medical Services, Bikenibeu, Tarawa, Kiribati.
Caroline LeeUniversity of New South Wales, Sydney, New South Wales, Australia.
Margaret Sue HuntleyHepatitis B Free, Sydney, New South Wales, Australia.
David C HilmersBaylor College of Medicine, Departments of Internal Medicine, Pediatrics, Space Medicine and Global Initiatives, Houston, Texas, United States of America.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

problemOver 290 million people worldwide suffer from chronic hepatitis B (CHB), with the highest prevalence in the Pacific islands. Mortality attributable to this disease exceeds that from HIV, tuberculosis and malaria combined in this region. CONTEXT: CHB is a major health problem in the Pacific island nation of Kiribati. Medical care is complicated by vast expanses of ocean separating population centres in its constituent islands. Birth-dose hepatitis B immunization rates need improvement. High rates of obesity, metabolic syndrome, and co-infection with hepatitis B and hepatitis D in Kiribati make treatment less effective. Staff allocation, training and retention are difficult. Limited infrastructure creates challenges in training, communications, laboratory testing and record-keeping. ACTION: We have established a CHB treatment programme in Kiribati based on World Health Organization (WHO) guidelines and local needs. It includes direct patient care; laboratory, radiology and pharmacy support; public education; training; and data management. Thousands of individuals have been screened, and 845 hepatitis B-positive patients have had blood sent to Australia for molecular testing. Patient education pamphlets, medical training programmes and treatment protocols have been developed. Seventy-nine patients have started treatment. Regular onsite visits by technical experts are scheduled throughout the year. LESSONS LEARNT AND DISCUSSION: This is the first national CHB treatment programme established in the Pacific islands region. Unique challenges exist in Kiribati, as they do in each nation affected by CHB. Close engagement with local partners, knowledge of the barriers involved, flexibility, advocacy, and support from WHO and volunteer technical experts are key attributes of a successful treatment programme.

Indexed as

AdultFemaleHepatitis B, ChronicHumansMaleMicronesiaMiddle AgedProgram EvaluationTreatment OutcomeYoung Adult

Identifiers

PMID33936856
PMCPMC8053900

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.