Evidence map›Paper›PMID 33936850›Full record

ArticleFood science and biotechnology2021

Combination of vegetable soup and glucan demonstrates synergistic effects on macrophage-mediated immune responses.

Ha-Nul Lee, Joo-Hee Choi, Ji-Yeon Park, Jae-Hun Ahn, Da Eun Jang, Jae Gun Shim, Jong-Hwan Park, Young-Min Kim

Open access · hybridAbstract read
In one paragraph

Article in Food science and biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Ha-Nul LeeDepartment of Integrative Food, Bioscience and Biotechnology, Chonnam National University, Gwangju, 61186 Republic of Korea.
Joo-Hee ChoiLaboratory Animal Medicine, College of Veterinary Medicine, Chonnam National University, Gwangju, 61186 Republic of Korea.
Ji-Yeon ParkLaboratory Animal Medicine, College of Veterinary Medicine, Chonnam National University, Gwangju, 61186 Republic of Korea.
Jae-Hun AhnLaboratory Animal Medicine, College of Veterinary Medicine, Chonnam National University, Gwangju, 61186 Republic of Korea.
Da Eun JangCharmden Health Sciences Agricultural Co. 152, Nanosandan-ro, Jinwon-myeon, Jangseong-gun, Jeollanam-do Republic of Korea.
Jae Gun ShimCharmden Health Sciences Agricultural Co. 152, Nanosandan-ro, Jinwon-myeon, Jangseong-gun, Jeollanam-do Republic of Korea.
Jong-Hwan ParkLaboratory Animal Medicine, College of Veterinary Medicine, Chonnam National University, Gwangju, 61186 Republic of Korea.
Young-Min KimDepartment of Integrative Food, Bioscience and Biotechnology, Chonnam National University, Gwangju, 61186 Republic of Korea.ORCID 0000-0002-2559-9182
Chonnam National University · KRJINIS Biopharmaceuticals (South Korea) · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vegetable soup (VS), a plant-based functional food, has been used as a traditional folk medicine and is attracting attention for its ability to enhance the immune response. β-Glucan, a well-established and effective immunomodulator, has synergistic effects when used in combination with some bioactive compounds. In the present study, we aimed to evaluate the synergistic immunomodulatory effects of the combination of VS and β-glucan on macrophage-mediated immune responses. β-Glucan was demonstrated to synergistically enhance the VS-stimulated immune response, including the production of interleukin-6, tumor necrosis factor-α, and nitric oxide, mainly through the mitogen-activated protein kinase pathway in macrophages. In addition, this combination has the potential for further development in functional foods with immune-enhancing activity. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s10068-021-00888-x.

Indexed as

Immune responseMitogen-activated protein kinaseSynergistic effectVegetable soupβ-glucan

Identifiers

PMID33936850
PMCPMC8050188
OpenAlexW3136872632

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.