Evidence map›Paper›PMID 33936587›Full record

ArticleJournal of surgical case reports2021

Thyroid paraganglioma in a patient with a history of carotid and vagal paraganglioma: metastatic or primary tumor?

Natesh Yepuri, Gautam R Vanga, Rana Naous, Sudhakar Kinthala

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PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of surgical case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 92% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Natesh YepuriDepartment of Surgery, SUNY Upstate Medical University, Syracuse, NY 13210, USA.
Gautam R VangaDepartment of Surgery, SUNY Upstate Medical University, Syracuse, NY 13210, USA.
Rana NaousDepartment of Pathology, SUNY Upstate Medical University, Syracuse, NY 13210, USA.
Sudhakar KinthalaDepartment of Anesthesiology, Robert Packer Hospital, Sayre, PA 18840, USA.
SUNY Upstate Medical University · USGuthrie Robert Packer Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Paragangliomas (PGs) are extremely rare multicentric neoplasms. Hereditary or familial PGs are associated with germline mutations in succinate dehydrogenase genes, seen in one-third of cases. Primary PGs of the thyroid are uncommon neuroendocrine neoplasms that account for 0.012% of all head and neck lesions. Although majority of these tumors are solitary, familial PGs are associated with synchronous tumors (carotid/vagal). We report an interesting case of primary thyroid PG in a patient with a previous history of a right carotid body, right vagal PGs and positive familial history, confining the differential diagnosis to recurrent lesions, which is the most common occurrence or new primary or a metastatic lesion. However, long interval and surgical anatomy suggests the diagnosis to be a primary lesion. In conclusion, although these lesions present multicentrically present at varying intervals, their occurrence at anatomically distinct sites should raise the concern for a new primary PG.

Indexed as

FamilialMetastaticParagangliomaPrimarySuccinate dehydrogenase (SDH) genesThyroid

Identifiers

PMID33936587
PMCPMC8062116
OpenAlexW3159108368

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.