Evidence map›Paper›PMID 33936520›Full record

ArticleAMIA ... Annual Symposium proceedings. AMIA Symposium2020

Normalizing Clinical Document Titles to LOINC Document Ontology: an Initial Study.

Xu Zuo, Jianfu Li, Bo Zhao, Yujia Zhou, Xiao Dong, Jon Duke, Karthik Natarajan, George Hripcsak, Nigam Shah, Juan M Banda and 3 more

Abstract read
In one paragraph

Article in AMIA ... Annual Symposium proceedings. AMIA Symposium, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Mapping Clinical Documents to theAMIA ... Annual Symposium proceedings. AMIA Symposium · 2023
    Article
  5. Article
  6. Logical Observation Identifiers Names and Codes (LOINCDiagnostics (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Xu ZuoSchool of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, TX, USA.
Jianfu LiSchool of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, TX, USA.
Bo ZhaoSchool of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, TX, USA.
Yujia ZhouSchool of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, TX, USA.
Xiao DongSchool of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, TX, USA.
Jon DukeGeorgia Institute of Technology, Atlanta, GA, USA.
Karthik NatarajanColumbia University, New York City, NY, USA.
George HripcsakColumbia University, New York City, NY, USA.
Nigam ShahStanford University, Stanford, CA, USA.
Juan M BandaGeorgia State University, Atlanta, GA, USA.
Ruth ReevesDepartment of Veterans Affairs, Tennessee Valley Healthcare System, Nashville, TN, USA.
Timothy MillerBoston Children's Hospital, Boston, MA, USA.
Hua XuSchool of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, TX, USA.

Funding

Open Health Natural Language Processing CollaboratoryU01TR002062 · NCATS · MAYO CLINIC ROCHESTER · PI JIANG, XIAOQIAN, LIU, HONGFANG · 2017 to 2021
$7.6M
Advancing Cancer Pharmacoepidemiology Research Through EHRs and InformaticsU24CA194215 · NCI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI TAO, CUI, YANG, PING · 2016 to 2020
$3.3M
NCATS NIH HHS U01 TR002062NCI NIH HHS U24 CA194215
6 · The paper itself

Abstract

The normalization of clinical documents is essential for health information management with the enormous amount of clinical documentation generated each year. The LOINC Document Ontology (DO) is a universal clinical document standard in a hierarchical structure. The objective of this study is to investigate the feasibility and generalizability of LOINC DO by mapping from clinical note titles across five institutions to five DO axes. We first developed an annotation framework based on the definition of LOINC DO axes and manually mapped 4,000 titles. Then we introduced a pre-trained deep learning model named Bidirectional Encoder Representations from Transformers (BERT) to enable automatic mapping from titles to LOINC DO axes. The results showed that the BERT-based automatic mapping achieved improved performance compared with the baseline model. By analyzing both manual annotations and predicted results, ambiguities in LOINC DO axes definition were discussed.

Indexed as

Logical Observation Identifiers Names and Codes

Identifiers

PMID33936520
PMCPMC8075502

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.