ArticleAMIA ... Annual Symposium proceedings. AMIA Symposium2020
Three Data-Driven Phenotypes of Multiple Organ Dysfunction Syndrome Preserved from Early Childhood to Middle Adulthood.
Article in AMIA ... Annual Symposium proceedings. AMIA Symposium, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.
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- Machine learning-based mortality prediction in critically ill patients with hypertension: comparative analysis, fairness, and interpretability.Frontiers in artificial intelligence · 2025Article
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- Predicting survival time for critically ill patients with heart failure using conformalized survival analysis.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2025Article
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Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Multiple organ dysfunction syndrome (MODS) is one of the major causes of death and long-term impairment in critically ill patients. MODS is a complex, heterogeneous syndrome consisting of different phenotypes, which has limited the development of MODS-specific therapies and prognostic models. We used an unsupervised learning approach to derive novel phenotypes of MODS based on the type and severity of six individual organ dysfunctions. In a large, multi-center cohort of pediatric, young and middle-aged adults admitted to three different intensive care units, we uncovered and characterized three distinct data-driven phenotypes of MODS which were reproducible across age groups, where independently associated with outcomes and had unique predictors of in-hospital mortality.
Indexed as
Identifiers
33936511PMC8075454W3157485412What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.