Evidence map›Paper›PMID 33936508›Full record

ArticleAMIA ... Annual Symposium proceedings. AMIA Symposium2020

The Centroid Cannot Hold: Comparing Sequential and Global Estimates of Coherence as Indicators of Formal Thought Disorder.

Weizhe Xu, Jake Portanova, Ayesha Chander, Dror Ben-Zeev, Trevor Cohen

Open access · greenAbstract readComparative Study
In one paragraph

Article in AMIA ... Annual Symposium proceedings. AMIA Symposium, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. An End-to-End Overview of Clinical Speech AI.IEEE transactions on audio, speech, and language processing (2025) · 2026
    Article
  4. Article
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  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Weizhe XuBiomedical Informatics and Medical Education.
Jake PortanovaBiomedical Informatics and Medical Education.
Ayesha ChanderEngineering (BRiTE) Center, Psychiatry and Behavioral Sciences; University of Washington, Seattle, WA.
Dror Ben-ZeevBiomedical Informatics and Medical Education.
Trevor CohenBiomedical Informatics and Medical Education.
Institute for Medical Informatics and Biostatistics · CHUniversity of Washington · US

Funding

Mobile RDoC: Using Smartphone Technology to Understand Auditory Verbal HallucinationsR01MH112641 · NIMH · UNIVERSITY OF WASHINGTON · PI BEN-ZEEV, DROR · 2017 to 2020
$2.8M
NIMH NIH HHS R01 MH112641
6 · The paper itself

Abstract

Thought disorder (TD) as reflected in incoherent speech is a cardinal symptom of schizophrenia and related disorders. Quantification of the degree ofTD can inform diagnosis, monitoring, and timely intervention. Consequently, there has been an interest in applying methods ofdistributional semantics to quantify incoherence ofspoken language. Prior studies have generally involved few participants and utilized speech data collected in on-site structured interviews. In this paper we conduct a comprehensive evaluation ofapproaches to quantify incoherence using distributional semantics, including a novel variant that measures the global coherence oftext. This evaluation is conducted in the context of "audio diaries" collected from participants experiencing auditory verbal hallucinations using a smartphone application. Results reveal our novel global coherence metric using the centroid (weighted vector average) outperforms established approaches in their agreement with human annotators, supporting their preferential use in the context of short recordings ofunstructured and largely spontaneous speech.

Indexed as

SemanticsAdultFemaleHallucinationsHumansMaleMiddle AgedSchizophreniaSense of CoherenceSpeechYoung Adult

Identifiers

PMID33936508
PMCPMC8075468
OpenAlexW3157868277

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.