Evidence map›Paper›PMID 33936474›Full record

Observational studyAMIA ... Annual Symposium proceedings. AMIA Symposium2020

Characterizing database granularity using SNOMED-CT hierarchy.

Anna Ostropolets, Christian Reich, Patrick Ryan, Chunhua Weng, Anthony Molinaro, Frank DeFalco, Jitendra Jonnagaddala, Siaw-Teng Liaw, Hokyun Jeon, Rae Woong Park and 9 more

Open access · greenAbstract readObservational Study
In one paragraph

Observational study in AMIA ... Annual Symposium proceedings. AMIA Symposium, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Phenotyping in distributed data networks: selecting the right codes for the right patients.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 6 institutions in 2 countries.

Anna OstropoletsColumbia University, New York, NY, USA.
Christian ReichIQVIA, Cambridge, MA, USA.
Patrick RyanColumbia University, New York, NY, USA.
Chunhua WengColumbia University, New York, NY, USA.
Anthony MolinaroJanssen Epidemiology Analytics, Janssen Research & Development, Titusville, NJ, USA.
Frank DeFalcoJanssen Epidemiology Analytics, Janssen Research & Development, Titusville, NJ, USA.
Jitendra JonnagaddalaUniversity of New South Wales Sydney, Australia.
Siaw-Teng LiawUniversity of New South Wales Sydney, Australia.
Hokyun JeonAjou University Graduate School of Medicine, Suwon, Gyeonggi-do, Republic of Korea.
Rae Woong ParkAjou University Graduate School of Medicine, Suwon, Gyeonggi-do, Republic of Korea.
Matthew E SpotnitzColumbia University, New York, NY, USA.
Karthik NatarajanColumbia University, New York, NY, USA.
George ArgyriouIQVIA, Cambridge, MA, USA.
Kristin KostkaIQVIA, Cambridge, MA, USA.
Robert MillerTufts Medical Center, Institute for Clinical Research and Health Policy Studies, Boston, MA, USA.
Andrew WilliamsTufts Medical Center, Institute for Clinical Research and Health Policy Studies, Boston, MA, USA.
Evan MintyO'Brien Centre for Population Health, Faculty of Medicine, University of Calgary, Canada.
Jose PosadaStanford Center for Biomedical Informatics Research, Stanford, CA, USA.
George HripcsakColumbia University, New York, NY, USA.
Columbia University · USIQVIA (United States) · USTufts Medical Center · USUNSW Sydney · AUNewYork–Presbyterian Hospital · USStanford Medicine · US

Funding

Training in Biomedical Informatics at Columbia UniversityT15LM007079 · NLM · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI NOEMIE ELHADAD, GEORGE M HRIPCSAK · 1992 to 2026
$28.9M
DISCOVERING AND APPLYING KNOWLEDGE IN CLINICAL DATABASESR01LM006910 · NLM · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI HRIPCSAK, GEORGE M · 2000 to 2023
$10.6M
Bridging the Semantic Gap Between Research Eligibility Criteria and Clinical DataR01LM009886 · NLM · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI WENG, CHUNHUA · 2009 to 2020
$5.3M
NLM NIH HHS R01 LM006910NLM NIH HHS R01 LM009886NLM NIH HHS T15 LM007079
6 · The paper itself

Abstract

Multi-center observational studies require recognition and reconciliation of differences in patient representations arising from underlying populations, disparate coding practices and specifics of data capture. This leads to different granularity or detail of concepts representing the clinical facts. For researchers studying certain populations of interest, it is important to ensure that concepts at the right level are used for the definition of these populations. We studied the granularity of concepts within 22 data sources in the OHDSI network and calculated a composite granularity score for each dataset. Three alternative SNOMED-based approaches for such score showed consistency in classifying data sources into three levels of granularity (low, moderate and high), which correlated with the provenance of data and country of origin. However, they performed unsatisfactorily in ordering data sources within these groups and showed inconsistency for small data sources. Further studies on examining approaches to data source granularity are needed.

Indexed as

Systematized Nomenclature of MedicineDatabases, FactualHumansInformation Storage and Retrieval

Identifiers

PMID33936474
PMCPMC8075504
OpenAlexW3158004672

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.