Evidence map›Paper›PMID 33936461›Full record

ArticleAMIA ... Annual Symposium proceedings. AMIA Symposium2020

Bleeding Entity Recognition in Electronic Health Records: A Comprehensive Analysis of End-to-End Systems.

Avijit Mitra, Bhanu Pratap Singh Rawat, David McManus, Alok Kapoor, Hong Yu

Open access · greenAbstract read
In one paragraph

Article in AMIA ... Annual Symposium proceedings. AMIA Symposium, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Natural Language Processing andJMIR medical informatics · 2025
    Article
  4. Review
  5. Article
  6. Machine learning approaches for electronic health records phenotyping: a methodical review.Journal of the American Medical Informatics Association : JAMIA · 2023
    Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Avijit MitraCollege of Information and Computer Science, University of Massachusetts Amherst, Amherst, MA, United States.
Bhanu Pratap Singh RawatCollege of Information and Computer Science, University of Massachusetts Amherst, Amherst, MA, United States.
David McManusDepartment of Medicine, University of Massachusetts Medical School, Worcester, MA, United States.
Alok KapoorDepartment of Medicine, University of Massachusetts Medical School, Worcester, MA, United States.
Hong YuCollege of Information and Computer Science, University of Massachusetts Amherst, Amherst, MA, United States.
Amherst College · USUniversity of Massachusetts Chan Medical School · USUniversity of Massachusetts Amherst · US

Funding

EHR Anticoagulants PharmacovigilanceR01HL125089 · NHLBI · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI YU, HONG · 2015 to 2019
$4.9M
NHLBI NIH HHS R01 HL125089
6 · The paper itself

Abstract

A bleeding event is a common adverse drug reaction amongst patients on anticoagulation and factors critically into a clinician's decision to prescribe or continue anticoagulation for atrial fibrillation. However, bleeding events are not uniformly captured in the administrative data of electronic health records (EHR). As manual review is prohibitively expensive, we investigate the effectiveness of various natural language processing (NLP) methods for automatic extraction of bleeding events. Using our expert-annotated 1,079 de-identified EHR notes, we evaluated state-of-the-art NLP models such as biLSTM-CRF with language modeling, and different BERT variants for six entity types. On our dataset, the biLSTM-CRF surpassed other models resulting in a macro F1-score of 0.75 whereas the performance difference is negligible for sentence and document-level predictions with the best macro F1-scores of 0.84 and 0.96, respectively. Our error analyses suggest that the models' incorrect predictions can be attributed to variability in entity spans, memorization, and missing negation signals.

Indexed as

Drug-Related Side Effects and Adverse ReactionsElectronic Health RecordsHemorrhageHumansLanguageNatural Language Processing

Identifiers

PMID33936461
PMCPMC8075442
OpenAlexW3157030838

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.