SynthesisAMIA ... Annual Symposium proceedings. AMIA Symposium2020
Conversational Agents for Chronic Disease Self-Management: A Systematic Review.
Synthesis in AMIA ... Annual Symposium proceedings. AMIA Symposium, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 5 syntheses or guidelines pooled it, 31 citations in OpenAlex.
- Usability and User Experience Assessment of Health Care Conversational Agents Using Validated Subjective Instruments: Systematic Review and Comparative Analysis.JMIR human factors · 2026Pooled it
- Conversational Agents Supporting Self-Management in People With a Chronic Disease: Systematic Review.Journal of medical Internet research · 2025Pooled it
- Families' Experiences With Family-Focused Web-Based Interventions for Improving Health: Qualitative Systematic Literature Review.Journal of medical Internet research · 2025Pooled it
- A systematic review of artificial intelligence-powered (AI-powered) chatbot intervention for managing chronic illness.Annals of medicine · 2024Pooled it
- A Systematic Review on Healthcare Artificial Intelligent Conversational Agents for Chronic Conditions.Sensors (Basel, Switzerland) · 2022Pooled it
- Effectiveness of Conversational Agents on Patient-Reported Outcomes in Chronic Pain Management: A Systematic Review and Meta-Analysis.Healthcare (Basel, Switzerland) · 2026Review
- "Your Digital Doctor Will Now See You": A Narrative Review of VR and AI Technology in Chronic Illness Management.Healthcare (Basel, Switzerland) · 2026Review
- Determining the Feasibility and Usability of a Co-Designed Culturally Appropriate Conversational Agent (DESI-Heart) to Support Self-Care in People With Cardiovascular Diseases: Protocol for a Single-Arm Pilot Trial.JMIR research protocols · 2025Article
- Chronic Illnesses: Varied Health Patterns and Mental Health Challenges.Healthcare (Basel, Switzerland) · 2025Article
- User Engagement with A Multimodal Conversational Agent for Self-Care and Chronic Disease Management: A Retrospective Analysis.Journal of medical systems · 2025Article
- Effectiveness of Chatbot interventions for reducing caregiver burden: Protocol for a systematic review and meta-analysis.MethodsX · 2025Article
- Exploring the Role of Voice Assistants in Managing Noncommunicable Diseases: A Systematic Review on Clinical, Behavioral Outcomes, Quality of Life, and User Experiences.Healthcare (Basel, Switzerland) · 2025Review
- The first AI-based Chatbot to promote HIV self-management: A mixed methods usability study.HIV medicine · 2025Article
- Barriers to effective management of type 2 diabetes mellitus in primary healthcare facilities.Journal of public health in Africa · 2025Article
- Needs-Assessment for an Artificial Intelligence-Based Chatbot for Pharmacists in HIV Care: Results from a Knowledge-Attitudes-Practices Survey.Healthcare (Basel, Switzerland) · 2024Article
- Engagement With Conversational Agent-Enabled Interventions in Cardiometabolic Disease Management: Protocol for a Systematic Review.JMIR research protocols · 2024Article
- AI Hesitancy and Acceptability-Perceptions of AI Chatbots for Chronic Health Management and Long COVID Support: Survey Study.JMIR human factors · 2024Article
- Evaluating the Potential and Pitfalls of AI-Powered Conversational Agents as Humanlike Virtual Health Carers in the Remote Management of Noncommunicable Diseases: Scoping Review.Journal of medical Internet research · 2024Article
- Infusing behavior science into large language models for activity coaching.PLOS digital health · 2024Article
- Adapting and Evaluating an AI-Based Chatbot Through Patient and Stakeholder Engagement to Provide Information for Different Health Conditions: Master Protocol for an Adaptive Platform Trial (the MARVIN Chatbots Study).JMIR research protocols · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
We conducted a systematic literature review to assess how conversational agents have been used to facilitate chronic disease self-management. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) framework was used. Literature was searched across five databases, and we included full-text articles that contained primary research findings for text-based conversational agents focused on self-management for chronic diseases in adults. 1,606 studies were identified, and 12 met inclusion criteria. Outcomes were largely focused on usability of conversational agents, and participants mostly reported positive attitudes with some concerns related to privacy and shallow content. In several studies, there were improvements on the Patient Health Questionnaire (p<0.05), Generalized Anxiety Disorder Scale (p=0.004), Perceived Stress Scale (p=0.048), Flourishing Scale (p=0.032), and Overall Anxiety Severity and Impairment Scale (p<0.05). There is early evidence that suggests conversational agents are acceptable, usable, and may be effective in supporting self-management, particularly for mental health.
Indexed as
Identifiers
33936424PMC8075433W3029938811What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.