Evidence map›Paper›PMID 33936396›Full record

ArticleAMIA ... Annual Symposium proceedings. AMIA Symposium2020

Deep Learning Approach to Parse Eligibility Criteria in Dietary Supplements Clinical Trials Following OMOP Common Data Model.

Anusha Bompelli, Jianfu Li, Yiqi Xu, Nan Wang, Yanshan Wang, Terrence Adam, Zhe He, Rui Zhang

Abstract read
In one paragraph

Article in AMIA ... Annual Symposium proceedings. AMIA Symposium, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Anusha BompelliInstitute for Health Informatics.
Jianfu LiUniversity of Texas Health Science Center, Houston, TX, USA.
Yiqi XuDepartment of Statistics, and.
Nan WangSchool of Statistics, and.
Yanshan WangDepartment of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
Terrence AdamInstitute for Health Informatics.
Zhe HeSchool of Information, Florida State University, Tallahassee, FL, USA.
Rui ZhangInstitute for Health Informatics.

Funding

Using social networks to map and evaluate team science across CTSA hubsUL1TR001427 · NCATS · UNIVERSITY OF FLORIDA · PI MITCHELL, DUANE A. · 2015 to 2024
$37.2M
University of Minnesota Clinical and Translational Science Institute (UMN CTSI)UL1TR002494 · NCATS · UNIVERSITY OF MINNESOTA · PI BLAZAR, BRUCE R, WEISDORF, DANIEL J · 2018 to 2022
$34.9M
A Translational Informatics Framework to Mine Efficacy and Safety of Dietary SupplementsR01AT009457 · NCCIH · UNIVERSITY OF MINNESOTA · PI RUI ZHANG · 2017 to 2026
$4.1M
Systematic Analysis of Clinical Study Generalizability Assessment Methods with InformaticsR21AG061431 · NIA · FLORIDA STATE UNIVERSITY · PI BIAN, JIANG, HE, ZHE · 2019 to 2020
$793k
NCATS NIH HHS UL1 TR001427NCATS NIH HHS UL1 TR002494NCCIH NIH HHS R01 AT009457NIA NIH HHS R21 AG061431
6 · The paper itself

Abstract

Dietary supplements (DSs) have been widely used in the U.S. and evaluated in clinical trials as potential interventions for various diseases. However, many clinical trials face challenges in recruiting enough eligible patients in a timely fashion, causing delays or even early termination. Using electronic health records to find eligible patients who meet clinical trial eligibility criteria has been shown as a promising way to assess recruitment feasibility and accelerate the recruitment process. In this study, we analyzed the eligibility criteria of 100 randomly selected DS clinical trials and identified both computable and non-computable criteria. We mapped annotated entities to OMOP Common Data Model (CDM) with novel entities (e.g., DS). We also evaluated a deep learning model (Bi-LSTM-CRF) for extracting these entities on CLAMP platform, with an average F1 measure of 0.601. This study shows the feasibility of automatic parsing of the eligibility criteria following OMOP CDM for future cohort identification.

Indexed as

Clinical Trials as TopicDeep LearningDietary SupplementsElectronic Health RecordsPatient SelectionDatabases, FactualFeasibility StudiesHumansModels, TheoreticalNatural Language ProcessingPartnership Practice

Identifiers

PMID33936396
PMCPMC8075443

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.