Evidence map›Paper›PMID 33936395›Full record

ArticleAMIA ... Annual Symposium proceedings. AMIA Symposium2020

Using Natural Language Processing and Machine Learning to Identify Hospitalized Patients with Opioid Use Disorder.

Suzanne V Blackley, Erin MacPhaul, Bianca Martin, Wenyu Song, Joji Suzuki, Li Zhou

Open access · greenAbstract read
In one paragraph

Article in AMIA ... Annual Symposium proceedings. AMIA Symposium, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 26 citations in OpenAlex.

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  11. Detecting Opioid Use Disorder in Health Claims Data With Positive Unlabeled Learning.IEEE journal of biomedical and health informatics · 2025
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  14. ODD: A Benchmark Dataset for the Natural Language Processing Based Opioid Related Aberrant Behavior Detection.Proceedings of the conference. Association for Computational Linguistics. North American Chapter. Meeting · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Suzanne V BlackleyClinical and Quality Analysis, Information Systems, Mass General Brigham, Boston, MA, USA.
Erin MacPhaulDivision of General Medicine and Primary Care, Brigham and Women's Hospital, Boston, MA, USA.
Bianca MartinDepartment of Psychiatry, Brigham and Women's Hospital, Boston, MA, USA.
Wenyu SongDivision of General Medicine and Primary Care, Brigham and Women's Hospital, Boston, MA, USA.
Joji SuzukiDepartment of Psychiatry, Brigham and Women's Hospital, Boston, MA, USA.
Li ZhouDivision of General Medicine and Primary Care, Brigham and Women's Hospital, Boston, MA, USA.
Brigham and Women's Hospital · USHarvard University · USMass General Brigham · US

Funding

Initiating substance use disorder treatment in hospitalized opioid use disorder patientsK23DA042326 · NIDA · BRIGHAM AND WOMEN'S HOSPITAL · PI SUZUKI, JOJI · 2017 to 2021
$999k
NIDA NIH HHS K23 DA042326
6 · The paper itself

Abstract

Opioid use disorder (OUD) represents a global public health crisis that challenges classic clinical decision making. As existing hospital screening methods are resource-intensive, patients with OUD are significantly under-detected. An automated and accurate approach is needed to improve OUD identification so that appropriate care can be provided to these patients in a timely fashion. In this study, we used a large-scale clinical database from Mass General Brigham (MGB; formerly Partners HealthCare) to develop an OUD patient identification algorithm, using multiple machine learning methods. Working closely with an addiction psychiatrist, we developed a set of hand-crafted rules for identifying information suggestive of OUD from free-text clinical notes. We implemented a natural language processing (NLP)-based classification algorithm within the Medical Text Extraction, Reasoning and Mapping System (MTERMS) tool suite to automatically label patients as positive or negative for OUD based on these rules. We further used the NLP output as features to build multiple machine learning and a neural classifier. Our methods yielded robust performance for classifying hospitalized patients as positive or negative for OUD, with the best performing feature set and model combination achieving an F1 score of 0.97. These results show promise for the future development of a real-time tool for quickly and accurately identifying patients with OUD in the hospital setting.

Indexed as

Clinical Decision-MakingMachine LearningNatural Language ProcessingAlgorithmsHumansOpioid-Related Disorders

Identifiers

PMID33936395
PMCPMC8075424
OpenAlexW3157176745

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.