Evidence map›Paper›PMID 33936350›Full record

Trial reportPain research & management2021

Effects of Propofol versus Sevoflurane on Postoperative Pain and Neuroendocrine Stress Response in Oocyte Pickup Patients.

Yavuz Orak, Fatma İnanç Tolun, Murat Bakacak, Aslı Yaylalı, Hakan Kıran, Hafize Öksüz, Adem Doğaner, Işıl Yağmur, Ahmet Altun

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Pain research & management, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Yavuz OrakDepartment of Anesthesiology and Reanimation, Kahramanmaras Sutcu Imam University, Kahramanmaras, Turkey.ORCID 0000-0002-8356-6223
Fatma İnanç TolunDepartment of Biochemistry, Kahramanmaras Sutcu Imam University, Kahramanmaras, Turkey.ORCID 0000-0002-1157-2958
Murat BakacakDepartment of Obstetrics and Gynecology, Kahramanmaras Sutcu Imam University, Kahramanmaras, Turkey.ORCID 0000-0001-8982-5401
Aslı YaylalıHistology Department, Kahramanmaras Sutcu Imam University, Kahramanmaras, Turkey.ORCID 0000-0003-2360-5320
Hakan KıranDepartment of Obstetrics and Gynecology, Kahramanmaras Sutcu Imam University, Kahramanmaras, Turkey.ORCID 0000-0003-3032-5861
Hafize ÖksüzDepartment of Anesthesiology and Reanimation, Kahramanmaras Sutcu Imam University, Kahramanmaras, Turkey.ORCID 0000-0001-5963-6861
Adem DoğanerBiostatistics and Medical Informatics, Kahramanmaras Sutcu Imam University, Kahramanmaras, Turkey.ORCID 0000-0002-0270-9350
Işıl YağmurDepartment of Biochemistry, Kahramanmaras Sutcu Imam University, Kahramanmaras, Turkey.ORCID 0000-0002-7009-4693
Ahmet AltunDepartment of Pharmacology, Sivas Cumhuriyet University, Sivas, Turkey.ORCID 0000-0003-2056-8683
Kahramanmaraş Sütçü İmam University · TRSivas Cumhuriyet Üniversitesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Pain aggravates the autonomic response to stress and raises neuroendocrine stress hormone levels. We compared the effects of propofol and sevoflurane on postoperative pain and neuroendocrine stress hormones. A prospective, randomized, and controlled trial was conducted with 60 patients. Methods: We randomly allocated patients to groups P (remifentanil/propofol, Result: Demographic data were similar. The preoperative serum aldosterone levels were significantly higher in group P ( Conclusion: The effects of anesthetic agents were different. In group P, in the preoperative and postoperative evaluation, ACTH, glucagon, and PGE2 increased postoperatively, while cortisol decreased. In group S, aldosterone and CRH increased postoperatively. Glucagon and PG E2 were higher in group P than S, postoperatively.

Indexed as

AdolescentAdultAnesthetics, InhalationFemaleHumansMaleNeurosecretory SystemsOocyte RetrievalPostoperative PainPropofolProspective StudiesSevofluraneYoung AdultAnesthetics, InhalationPropofolSevoflurane

Identifiers

PMID33936350
PMCPMC8055426
OpenAlexW3155452537

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.