ArticleJournal of pediatric neurosciences
Various Neurological Symptoms with Vitamin B12 Deficiency and Posttreatment Evaluation.
Article in Journal of pediatric neurosciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
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Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.
- Efficacy of sublingual and oral vitamin B12 versus intramuscular administration: insights from a systematic review and meta-analysis.Frontiers in pharmacology · 2025Pooled it
- Importance of Vitamin Supplementation During Pregnancy: Pancytopenia in a 3-Month-Old Neonate.Reports (MDPI) · 2026Article
- A Novel Approach to the Management of Children with Primary Nocturnal Enuresis.Children (Basel, Switzerland) · 2025Article
- The Neurological Sequelae of Vitamin B12 Deficiency: A Systematic Review and Randomized Controlled Trial.Cureus · 2025Review
- Neurological Implications of Vitamin B12 Deficiency in Diet: A Systematic Review and Meta-Analysis.Healthcare (Basel, Switzerland) · 2023Review
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundVitamin B12 deficiency occurs primarily as a result of insufficient dietary intake in children in developing countries. Vitamin B12 deficiency produces a cluster of neurological symptoms in children.
aimThe aim of this study was to describe the vitamin B12 status of patients who were admitted with neurological symptoms and to evaluate the clinical response to vitamin B12 treatment. MATERIALS AND
methodsThis study was conducted on children who had vitamin B12 deficiency presented with neurological findings from January 2014 to October 2016. Patients with serum vitamin B12 levels lower than 300 pg/mL received intramuscular or oral vitamin B12 treatment.
resultsThree hundred and fifty-one patients presenting with neurologic symptoms and who had low serum vitamin B12 deficiency were analyzed. Our study population was composed mainly of adolescent age. The most common symptom with respect to age was headache. In infant patients, most common symptoms were seizure and developmental delay.
conclusionEarly diagnosis and vitamin B12 treatment are advocated to avoid long-term injury. Our study shows that patients with serum vitamin B12 levels lower than 300 pg/mL showed clinical improvement of neurological symptoms after receiving vitamin B12 treatment.
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