Evidence map›Paper›PMID 33936218›Full record

ArticleJournal of exercise science and fitness2021

Plasma free metanephrine and normethanephrine levels correlated to plasma catecholamine after acute running in amateur runner.

Katsuyuki Tokinoya, Yasuhiro Shishikura, Nanami Sekine, Atsushi Aoyagi, Yasuko Yoshida, Yuichi Aita, Takehito Sugasawa, Yoshiharu Nabekura, Kazuhiro Takekoshi

Abstract readCase Reports
In one paragraph

Article in Journal of exercise science and fitness, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Katsuyuki TokinoyaFaculty of Medicine, University of Tsukuba, Ibaraki, Japan.
Yasuhiro ShishikuraGraduate School of Comprehensive Human Sciences, University of Tsukuba, Ibaraki, Japan.
Nanami SekineGraduate School of Comprehensive Human Sciences, University of Tsukuba, Ibaraki, Japan.
Atsushi AoyagiGraduate School of Comprehensive Human Sciences, University of Tsukuba, Ibaraki, Japan.
Yasuko YoshidaFaculty of Medicine, University of Tsukuba, Ibaraki, Japan.
Yuichi AitaFaculty of Medicine, University of Tsukuba, Ibaraki, Japan.
Takehito SugasawaFaculty of Medicine, University of Tsukuba, Ibaraki, Japan.
Yoshiharu NabekuraFaculty of Health and Sport Sciences, University of Tsukuba, Ibaraki, Japan.
Kazuhiro TakekoshiFaculty of Medicine, University of Tsukuba, Ibaraki, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCatecholamine is a typical index of exercise intensity, but it is difficult to detect. Plasma metanephrine (MN) and normethanephrine (NMN) levels are more stable than those of catecholamines. This study aimed to investigate plasma MN and NMN levels during acute exercise running in amateur runners.

methodsSamples were collected from eight healthy male participants. They were either sedentary or running at low or high intensity for 30 min. Blood samples were collected under these conditions. Measurements taken included plasma adrenaline, noradrenaline, MN, and NMN.

resultsPlasma adrenaline levels increased after high-intensity exercise compared with sedentary subjects. Plasma noradrenaline, MN, and NMN levels increased after both low- and high-intensity exercise compared with sedentary subjects. In addition, these levels were also significantly higher at high intensity than at low intensity. Plasma adrenaline and noradrenaline levels were positively correlated with plasma free MN and NMN levels after acute running, respectively.

conclusionThis study revealed that plasma MN and NMN levels transiently increased depending on exercise intensity in amateur runners. In addition, plasma NMN levels are better markers than plasma MN levels because of their stronger correlation with plasma catecholamine levels.

Indexed as

ExerciseIntensityRunningVentilatory threshold

Identifiers

PMID33936218
PMCPMC8055611

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.