ArticleJournal of tropical medicine2021
Thrombocytopenia as a Diagnostic Marker for Malaria in Patients with Acute Febrile Illness.
Article in Journal of tropical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- Prevalence of thrombocytopenia among patients with malaria in Ethiopia: a systematic review and metanalysis.Malaria journal · 2025Pooled it
- Inflammation and Routine Laboratory Associations in Imported Falciparum Malaria Assessed by Partial Correlation Analysis.Acta parasitologica · 2026Article
- Successful vaginal delivery in very severe malarial thrombocytopenia: a case report.Journal of medical case reports · 2026Article
- Association between thrombocytopaenia and Plasmodium falciparum infection in Ghana.Scientific reports · 2026Article
- Clinical Characteristics and Outcomes of Malaria Patients in the Aseer Region, Saudi Arabia: A Retrospective Study (2022-2025).Tropical medicine and infectious disease · 2026Article
- Profiling of circulating immune factors and host-derived extracellular vesicles in response to bacterial or malaria acute fever.Infection · 2026Article
- Prevalence and factors associated with severe thrombocytopenia among hospitalized patients with malaria attending Kigeme District Hospital, Southern Province, Rwanda: cross-sectional study.Malaria journal · 2025Article
- Variations in haematological and inflammatory biomarkers and their association with Plasmodium falciparum malaria: a cross-sectional comparative study at a clinic in Ghana.Malaria journal · 2025Article
- Thrombocytopenia in patients with Plasmodium vivax in Colombia is associated with anti-phosphatidylserine autoantibodies and IL-6, IFNγ, IL-10 and TGF-β.PLoS neglected tropical diseases · 2025Article
- A Rare Case of Hypoparathyroidism With Basal Ganglia Calcification in a 17-year-old Epileptic Patient Presenting With Falciparum Malaria, Thrombocytopenia and Anemia.Clinical medicine insights. Case reports · 2025Article
- Haematological abnormalities as diagnostic indicators of malaria in returning travellers: a retrospective study at Mohamed V Military Instruction Hospital.Access microbiology · 2025Article
- Hematological Profiles of Adults Coinfected With HIV and Malaria Receiving Highly Active Antiretroviral Therapy at Bonga Gebretsadik Shawo General Hospital, Southwest Ethiopia: A Comparative Cross-Sectional Study.Advances in hematology · 2025Article
- Clinical spectrum and complications ofMalariaWorld journal · 2025Article
- Platelet Ido1 expression is induced during Plasmodium yoelii infection, altering plasma tryptophan metabolites.Blood advances · 2024Article
- Locally acquired malaria: a retrospective analysis of long-term surveillance data, European France, 1995 to 2022.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2024Article
- Basic coagulation parameters and platelet count among malaria patients attending at Addis Zemen Primary Hospital, Northwest Ethiopia.BMC infectious diseases · 2024Article
- Challenges and Strategies in Administering Anesthesia to Pregnant Patients With Malaria: A Comprehensive Review.Cureus · 2024Review
- Haematological Profile in Patients With Acute Falciparum Malaria: A Hospital-Based Study.Cureus · 2024Article
- Malaria parasitaemia and its impact on biological parameters among children <16 years old attending the Nkwen District Hospital, Cameroon.MalariaWorld journal · 2024Article
- Clinical characteristics of platelet-mediated killing circulating parasite of major human malaria.Annals of medicine · 2023Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThrombocytopenia is the most common hematological abnormality in patients with acute malaria. This study aimed to determine the role of thrombocytopenia as a diagnostic marker for malaria in patients with acute febrile illness.
methodA cross-sectional health facility-based study was conducted on 423 consecutively selected acute febrile patients at Ataye District Hospital from February to May 2019 GC. A complete blood count and malaria microscopy were performed for each acute febrile patient. ROC curve analysis was performed to calculate sensitivity, specificity, positive predictive value, and negative predictive value of platelet count in predicting malaria. A
resultOut of the 423 acute febrile patients, 73 (17.3%) were microscopically confirmed malaria cases and the rest 350 (82.7%) patients had negative blood film results. Of the microscopically confirmed malaria cases, 55 (75.34%) were
conclusionMalaria is still among the major public health problems in the country. Thrombocytopenia is a very good discriminatory test for the presence or absence of malaria with 79.5% sensitivity and 86.3% specificity. Therefore, this may be used in addition to the clinical and microscopic parameters to heighten the suspicion of malaria.
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Registered trials
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