Evidence map›Paper›PMID 33936085›Full record

ArticleFrontiers in immunology2021

Potential Mimicry of Viral and Pancreatic β Cell Antigens Through Non-Spliced and

Michele Mishto, Artem Mansurkhodzhaev, Teresa Rodriguez-Calvo, Juliane Liepe

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Are There Indeed Spliced Peptides in the Immunopeptidome?Molecular & cellular proteomics : MCP · 2021
    Article
  9. Article
  10. Response: Commentary: AnFrontiers in immunology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Michele MishtoCentre for Inflammation Biology and Cancer Immunology (CIBCI) & Peter Gorer Department of Immunobiology, King's College London, London, United Kingdom.
Artem MansurkhodzhaevMax-Planck-Institute for Biophysical Chemistry, Göttingen, Germany.
Teresa Rodriguez-CalvoInstitute of Diabetes Research, Helmholtz Zentrum München, German Research Center for Environmental Health, Munich-Neuherberg, Germany.
Juliane LiepeMax-Planck-Institute for Biophysical Chemistry, Göttingen, Germany.
Max Planck Institute for Biophysical Chemistry · DEHelmholtz Zentrum München · DEKing's College London · GB

Funding

Cancer Research UK 29686Cancer Research UK C67500/A29686Department of Health
6 · The paper itself

Abstract

Increasing evidence suggests that post-translational peptide splicing can play a role in the immune response under pathological conditions. This seems to be particularly relevant in Type 1 Diabetes (T1D) since post-translationally spliced epitopes derived from T1D-associated antigens have been identified among those peptides bound to Human Leucocyte Antigen (HLA) class I and II complexes. Their immunogenicity has been confirmed through CD4

Indexed as

RNA SplicingAntigens, ViralAutoimmunityDiabetes Mellitus, Type 1Disease SusceptibilityEpitopes, T-LymphocyteHistocompatibility Antigens Class IHost-Pathogen InteractionsHumansInsulin-Secreting CellsModels, MolecularProtein BindingProtein ConformationStructure-Activity RelationshipAntigens, ViralEpitopes, T-LymphocyteHistocompatibility Antigens Class Iantigen presentationmimicryspliced peptidesT1Dtolerancevirus

Identifiers

PMID33936085
PMCPMC8082463
OpenAlexW3153736554

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.