Evidence map›Paper›PMID 33936067›Full record

ArticleFrontiers in immunology2021

Large-Scale Gene Expression Signatures Reveal a Microbicidal Pattern of Activation in

Thyago Leal-Calvo, Bruna Leticia Martins, Daniele Ferreira Bertoluci, Patricia Sammarco Rosa, Rodrigo Mendes de Camargo, Giovanna Vale Germano, Vania Nieto Brito de Souza, Ana Carla Pereira Latini, Milton Ozório Moraes

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Interplay among differential exposure toFrontiers in immunology · 2023
    Article
  7. Frontiers in microbiology · 2023
    Article
  8. Article
  9. Article
  10. Transcriptomic Analysis ofFrontiers in cellular and infection microbiology · 2021
    Article
  11. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Thyago Leal-CalvoLaboratório de Hanseníase, Instituto Oswaldo Cruz, FIOCRUZ, Rio de Janeiro, Brazil.
Bruna Leticia MartinsDivisão de Pesquisa e Ensino, Instituto Lauro de Souza Lima, Bauru, Brazil.
Daniele Ferreira BertoluciDivisão de Pesquisa e Ensino, Instituto Lauro de Souza Lima, Bauru, Brazil.
Patricia Sammarco RosaDivisão de Pesquisa e Ensino, Instituto Lauro de Souza Lima, Bauru, Brazil.
Rodrigo Mendes de CamargoDivisão de Pesquisa e Ensino, Instituto Lauro de Souza Lima, Bauru, Brazil.
Giovanna Vale GermanoDivisão de Pesquisa e Ensino, Instituto Lauro de Souza Lima, Bauru, Brazil.
Vania Nieto Brito de SouzaDivisão de Pesquisa e Ensino, Instituto Lauro de Souza Lima, Bauru, Brazil.
Ana Carla Pereira LatiniDivisão de Pesquisa e Ensino, Instituto Lauro de Souza Lima, Bauru, Brazil.
Milton Ozório MoraesLaboratório de Hanseníase, Instituto Oswaldo Cruz, FIOCRUZ, Rio de Janeiro, Brazil.
Universidade Estadual Paulista (Unesp) · BRInstituto Lauro de Souza Lima · BRFundação Oswaldo Cruz · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Leprosy is a disease with a clinical spectrum of presentations that is also manifested in diverse histological features. At one pole, lepromatous lesions (L-pole) have phagocytic foamy macrophages heavily parasitized with freely multiplying intracellular

Indexed as

TranscriptomeAdultBlood DonorsCell PolarityCells, CulturedFemaleHealthy VolunteersHumansImmunity, CellularLeprosy, LepromatousMacrophagesMaleMycobacterium lepraePolymorphism, Single NucleotideSchwann CellsYoung AdulteQTLshost-directed therapyleprosymacrophagesMycobacterium lepraeSNPstuberculosis

Identifiers

PMID33936067
PMCPMC8085500
OpenAlexW3152518976

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.