Evidence map›Paper›PMID 33935988›Full record

ArticleFrontiers in microbiology2021

The Potent Trypanocidal Effect of LQB303, a Novel Redox-Active Phenyl-Tert-Butyl-Nitrone Derivate That Causes Mitochondrial Collapse in

Carolina Machado Macedo, Francis Monique de Souza Saraiva, Jéssica Isis Oliveira Paula, Suelen de Brito Nascimento, Débora de Souza Dos Santos Costa, Paulo Roberto Ribeiro Costa, Ayres Guimarães Dias, Marcia Cristina Paes, Natália Pereira Nogueira

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
  3. Virulence · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Carolina Machado MacedoLaboratório de Interação de Tripanossomatídeos e Vetores, Departamento de Bioquímica, IBRAG - Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil.
Francis Monique de Souza SaraivaLaboratório de Interação de Tripanossomatídeos e Vetores, Departamento de Bioquímica, IBRAG - Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil.
Jéssica Isis Oliveira PaulaLaboratório de Interação de Tripanossomatídeos e Vetores, Departamento de Bioquímica, IBRAG - Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil.
Suelen de Brito NascimentoLaboratório de Interação de Tripanossomatídeos e Vetores, Departamento de Bioquímica, IBRAG - Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil.
Débora de Souza Dos Santos CostaDepartamento de Química Orgânica, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil.
Paulo Roberto Ribeiro CostaLaboratório de Química Bioorgânica, NPPN, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
Ayres Guimarães DiasDepartamento de Química Orgânica, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil.
Marcia Cristina PaesLaboratório de Interação de Tripanossomatídeos e Vetores, Departamento de Bioquímica, IBRAG - Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil.
Natália Pereira NogueiraLaboratório de Interação de Tripanossomatídeos e Vetores, Departamento de Bioquímica, IBRAG - Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil.
Universidade do Estado do Rio de Janeiro · BRUniversidade Federal do Rio de Janeiro · BRUniversidade Federal Fluminense · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chagas disease, which is caused by

Indexed as

bioenergeticschemotherapyhigh-resolution respirometrymitochondriontropical neglected diseaseTrypanosoma cruzi

Identifiers

PMID33935988
PMCPMC8081855
OpenAlexW3152497470

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.