Evidence map›Paper›PMID 33935819›Full record

ArticleFrontiers in psychiatry2021

Effects of 7.5% Carbon Dioxide and Nicotine Administration on Latent Inhibition.

Kiri T Granger, Jennifer Ferrar, Sheryl Caswell, Mark Haselgrove, Paula M Moran, Angela Attwood, Jennifer H Barnett

Open access · goldAbstract read
In one paragraph

Article in Frontiers in psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Kiri T GrangerCambridge Cognition, Cambridge, United Kingdom.
Jennifer FerrarCambridge Cognition, Cambridge, United Kingdom.
Sheryl CaswellCambridge Cognition, Cambridge, United Kingdom.
Mark HaselgroveSchool of Psychology, University of Nottingham, Nottingham, United Kingdom.
Paula M MoranSchool of Psychology, University of Nottingham, Nottingham, United Kingdom.
Angela AttwoodAlcohol & Tobacco Research Group, University of Bristol, Bristol, United Kingdom.
Jennifer H BarnettCambridge Cognition, Cambridge, United Kingdom.
Cambridge Cognition (United Kingdom) · GBUniversity of Bristol · GBUniversity of Nottingham · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stratified medicine approaches have potential to improve the efficacy of drug development for schizophrenia and other psychiatric conditions, as they have for oncology. Latent inhibition is a candidate biomarker as it demonstrates differential sensitivity to key symptoms and neurobiological abnormalities associated with schizophrenia. The aims of this research were to evaluate whether a novel latent inhibition task that is not confounded by alternative learning effects such as learned irrelevance, is sensitive to (1) an in-direct model relevant to psychosis [using 7.5% carbon dioxide (CO

Indexed as

biomarkercarbon dioxide challengelatent inhibitionnicotineschizophrenia

Identifiers

PMID33935819
PMCPMC8085318
OpenAlexW3154450349

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.