ReviewFrontiers in pharmacology2021
Chemical Authentication of Botanical Ingredients: A Review of Commercial Herbal Products.
Review in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed.
- Multi-Platform Metabolomics for Fraud Detection in Spices and Botanical Food Supplements: From Fingerprint Acquisition to Decision-Grade Evidence.Molecules (Basel, Switzerland) · 2026Review
- Hydrogels Activated with Plant Extracts/Bioactive Compounds for Cancer Treatment: From Design to Application.Gels (Basel, Switzerland) · 2026Review
- Cultivar to chemotype: characterizing complex botanicals with mass spectrometry metabolomics.Natural product reports · 2026Review
- Review
- Bridging Traditional Wisdom and Evidence-Based Pharmaceutics: Comprehensive Specification and Biological Activity of the Wannachawee Recipe for Psoriasis.Plants (Basel, Switzerland) · 2026Article
- Compendial Perspectives on Botanical Identity Testing.Journal of natural products · 2026Review
- From fragmented innovation to an integrated plant-to-product framework: integrated digital twins and artificial intelligence approaches in phytomedicine.Frontiers in pharmacology · 2026Article
- Regulatory and HTA framework for herbal medicines in Indonesia.Journal of pharmaceutical policy and practice · 2026Review
- Article
- Quality Control Strategies for Differentiation of Kalanchoe Species.Phytochemical analysis : PCA · 2025Article
- Advancing herbal medicine safety: the need for a global pharmacovigilance approach.Naunyn-Schmiedeberg's archives of pharmacology · 2025Review
- Development of molecular diagnostic methods to distinguish acerola species for quality assurance of food, dietary supplements and natural health products.Scientific reports · 2025Article
- Botanical Authenticity of Miraruira Sold in the Amazonas State, Brazil, Based on Chemical Profiling Using DI-MS and Chemometric Analyses.Plants (Basel, Switzerland) · 2025Article
- Reference materials for food authentication.Analytical and bioanalytical chemistry · 2025Review
- Flavonoids and Other Polyphenols: Bioactive Molecules from Traditional Medicine Recipes/Medicinal Plants and Their Potential for Phytopharmaceutical and Medical Application.Molecules (Basel, Switzerland) · 2024Review
- Comprehensive Analysis ofNutrients · 2024Article
- Advancing botanical safety: A strategy for selecting, sourcing, and characterizing botanicals for developing toxicological tools.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2024Article
- The contemporary nexus of medicines security and bioprospecting: a future perspective for prioritizing the patient.Natural products and bioprospecting · 2024Review
- Three-tiered authentication of herbal traditional Chinese medicine ingredients used in women's health provides progressive qualitative and quantitative insight.Frontiers in pharmacology · 2024Article
- Ethical considerations in the regulation and use of herbal medicines in the European Union.Frontiers in medical technology · 2024Review
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chemical methods are the most important and widely used traditional plant identification techniques recommended by national and international pharmacopoeias. We have reviewed the successful use of different chemical methods for the botanical authentication of 2,386 commercial herbal products, sold in 37 countries spread over six continents. The majority of the analyzed products were reported to be authentic (73%) but more than a quarter proved to be adulterated (27%). At a national level, the number of products and the adulteration proportions varied very widely. Yet, the adulteration reported for the four countries, from which more than 100 commercial products were purchased and their botanical ingredients chemically authenticated, was 37% (United Kingdom), 31% (Italy), 27% (United States), and 21% (China). Simple or hyphenated chemical analytical techniques have identified the total absence of labeled botanical ingredients, substitution with closely related or unrelated species, the use of biological filler material, and the hidden presence of regulated, forbidden or allergenic species. Additionally, affecting the safety and efficacy of the commercial herbal products, other low quality aspects were reported: considerable variability of the labeled metabolic profile and/or phytochemical content, significant product-to-product variation of botanical ingredients or even between batches by the same manufacturer, and misleading quality and quantity label claims. Choosing an appropriate chemical technique can be the only possibility for assessing the botanical authenticity of samples which have lost their diagnostic microscopic characteristics or were processed so that DNA cannot be adequately recovered.
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