Evidence map›Paper›PMID 33935767›Full record

ArticleFrontiers in pharmacology2021

Adenosine and Kynurenic Acid Interactions: Possible Relevance for Schizophrenia Treatment?

Sarah Beggiato, Mariachiara Zuccarini, Tommaso Cassano, Dasiel Oscar Borroto-Escuela, Patrizia Di Iorio, Robert Schwarcz, Kjell Fuxe, Luca Ferraro

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 61% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 3 countries.

Sarah BeggiatoDepartment of Medical, Oral and Biotechnological Sciences, University of Chieti-Pescara, Chieti, Italy.
Mariachiara ZuccariniDepartment of Medical, Oral and Biotechnological Sciences, University of Chieti-Pescara, Chieti, Italy.
Tommaso CassanoDepartment of Medical and Surgical Sciences, University of Foggia, Foggia, Italy.
Dasiel Oscar Borroto-EscuelaDepartment of Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Patrizia Di IorioDepartment of Medical, Oral and Biotechnological Sciences, University of Chieti-Pescara, Chieti, Italy.
Robert SchwarczDepartment of Psychiatry, Maryland Psychiatric Research Center, University of Maryland School of Medicine, Baltimore, MD, United States.
Kjell FuxeDepartment of Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Luca FerraroDepartment of Life Sciences and Biotechnology and LTTA Center, University of Ferrara, Ferrara, Italy.
University of Chieti-Pescara · ITKarolinska Institutet · SEUniversity of Ferrara · ITUniversity of Foggia · ITUniversity of Maryland, Baltimore · US

Funding

The Effects of Kynurenine Aminotransferase Inhibition in People with SchizophreniaP50MH103222 · NIMH · UNIVERSITY OF MARYLAND BALTIMORE · PI SCHWARCZ, ROBERT · 2014 to 2023
$25.2M
NIMH NIH HHS P50 MH103222
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

adenosine A1 and A2A receptorscognitioncombinatory therapykynurenine pathwayreceptor heteromers

Identifiers

PMID33935767
PMCPMC8080066
OpenAlexW3155722897

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.