Evidence map›Paper›PMID 33935711›Full record

ArticleFrontiers in pharmacology2021

Pharmacokinetics, Bioavailability, Excretion and Metabolism Studies of Akebia Saponin D in Rats: Causes of the Ultra-Low Oral Bioavailability and Metabolic Pathway.

Pengfei Li, Jun Peng, Yuexin Li, Lili Gong, Yali Lv, He Liu, Tianhong Zhang, Song Yang, Hongchuan Liu, Jinglai Li and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Review
  7. Simultaneous Component Analysis ofPlants (Basel, Switzerland) · 2025
    Article
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Pengfei LiPharmacy Department of Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.
Jun PengGuollence Pharmaceutical Technology Co., Ltd., Beijing, China.
Yuexin LiSchool of Pharmacy, Shenyang Pharmaceutical University, Benxi City, China.
Lili GongPharmacy Department of Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.
Yali LvPharmacy Department of Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.
He LiuPharmacy Department of Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.
Tianhong ZhangGuollence Pharmaceutical Technology Co., Ltd., Beijing, China.
Song YangPharmacy Department of Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.
Hongchuan LiuPharmacy Department of Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.
Jinglai LiGuollence Pharmaceutical Technology Co., Ltd., Beijing, China.
Lihong LiuPharmacy Department of Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.
Beijing Chao-Yang Hospital · CNCapital Medical University · CNShenyang Pharmaceutical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Akebia saponin DbioavailabilityexcretionLC–MS/MSmetabolismpharmacokinetics

Identifiers

PMID33935711
PMCPMC8082176
OpenAlexW3156267333

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.