ArticleFrontiers in aging neuroscience2021
Investigating Neuroimaging Correlates of Early Frailty in Patients With Behavioral Variant Frontotemporal Dementia: A MRI and FDG-PET Study.
Article in Frontiers in aging neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 11 citations in OpenAlex.
- Towards a Multidimensional Model of Neurocognitive Disorders (MOND Model): Integrating Evidence from a Critical Review into a Model for Future Research.Journal of personalized medicine · 2026Review
- Neural embedding of frailty in cognitively unimpaired aging and dementia across Latin America.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Myocardial Inflammation as Key Mediator of Heart-brain Interaction After Myocardial Ischemia/Infarction: Mechanistic Exploration of Post-Myocardial Infarction Cognitive Dysfunction.Current neuropharmacology · 2026Review
- The predictive value of social cognition assessment for 1-year follow-up functional outcomes in behavioral variant frontotemporal dementia.Journal of neurology · 2025Article
- Neural correlates of frailty in cognitively healthy adults: A multimodal imaging study.PloS one · 2025Article
- Clinical relevance of disrupted topological organization of anatomical connectivity in behavioral variant frontotemporal dementia.Neurobiology of aging · 2023Article
- Heart failure and cognitive impairment: A narrative review of neuroimaging mechanism from the perspective of brain MRI.Frontiers in neuroscience · 2023Review
- Cognitive Dysfunction after Heart Disease: A Manifestation of the Heart-Brain Axis.Oxidative medicine and cellular longevity · 2021Review
- Investigating the Roles of Anterior Cingulate in Behavioral Variant Frontotemporal Dementia: A PET/MRI Study.Journal of Alzheimer's disease : JAD · 2021Article
- Editorial: Physical and Cognitive Frailty in the Elderly: An Interdisciplinary Approach.Frontiers in psychology · 2021Article
Corrections and comments
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Authors and funding
12 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Frailty is a dynamic clinical condition characterized by the reduction of interconnections among different psychobiological domains, which leads to a homeostatic vulnerability. The association between physical frailty and cognitive dysfunctions is a possible predictor of poor prognosis in patients with neurodegenerative disorders. However, this construct has not been fully analyzed by a multidimensional neuropsychogeriatric assessment matched with multimodal neuroimaging methods in patients with behavioral variant frontotemporal dementia (bvFTD). We have investigated cognitive dysfunctions and frailty status, assessed by both a neuropsychological evaluation and the Multidimensional Prognostic Index (MPI), in a sample of 18 bvFTD patients and compared to matched healthy controls. Gray matter (GM) volume (as assessed by voxel-based morphometry) and metabolism (on
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Registered trials
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