Evidence map›Paper›PMID 33935461›Full record

ArticleAnnals of dermatology2021

Cryosurgery as a Minimally Invasive Alternative Treatment for a Patient with Erosive Adenomatosis of the Nipple.

Kyung-Nam Bae, Kihyuk Shin, Woo-Il Kim, Min-Young Yang, Won-Ku Lee, Hoon-Soo Kim, Hyun-Chang Ko, Byung-Soo Kim, Moon-Bum Kim, Gun-Wook Kim

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Annals of dermatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Nipple Adenoma: Systematic Review of Literature.Plastic and reconstructive surgery. Global open · 2024
    Article
  2. Article
  3. Article
  4. Surgical management of erosive adenomatosis of the nipple: A case report.International journal of surgery case reports · 2021
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Kyung-Nam BaeDepartment of Dermatology, School of Medicine, Pusan National University, Busan, Korea.ORCID https://orcid.org/0000-0003-3254-8401
Kihyuk ShinDepartment of Dermatology, School of Medicine, Pusan National University, Busan, Korea.ORCID https://orcid.org/0000-0001-8955-9828
Woo-Il KimDepartment of Dermatology, School of Medicine, Pusan National University, Busan, Korea.ORCID https://orcid.org/0000-0001-7991-2827
Min-Young YangDepartment of Dermatology, School of Medicine, Pusan National University, Busan, Korea.ORCID https://orcid.org/0000-0001-8994-8401
Won-Ku LeeDepartment of Dermatology, School of Medicine, Pusan National University, Busan, Korea.ORCID https://orcid.org/0000-0002-4938-2455
Hoon-Soo KimDepartment of Dermatology, School of Medicine, Pusan National University, Busan, Korea.ORCID https://orcid.org/0000-0002-7649-1446
Hyun-Chang KoDepartment of Dermatology, School of Medicine, Pusan National University, Busan, Korea.ORCID https://orcid.org/0000-0002-3459-5474
Byung-Soo KimDepartment of Dermatology, School of Medicine, Pusan National University, Busan, Korea.ORCID https://orcid.org/0000-0003-0054-8570
Moon-Bum KimDepartment of Dermatology, School of Medicine, Pusan National University, Busan, Korea.ORCID https://orcid.org/0000-0003-4837-0214
Gun-Wook KimDepartment of Dermatology, College of Medicine, Dong-A University, Busan, Korea.ORCID https://orcid.org/0000-0003-1599-7045
Pusan National University · KRPusan National University Hospital · KRDong-A University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Erosive adenomatosis of the nipple (EAN), also known as nipple adenoma, florid papillomatosis, or papillary adenoma of the nipple, is a benign neoplasm originating from a lactiferous duct of the breast. Although the potential for malignant change is invariably negligible, the nature of the disease is quite intractable despite several treatment methods. Surgical excision is known as the treatment of choice, but this invasive approach is generally not acceptable to the vast majority of patients due to the cosmetic outcomes. Cryosurgery could be an alternative choice to preserve the structure of the nipple-areola complex, though its application has not been studied due to the paucity of cases. A 22-year-old female presented with a unilateral, crater-like erosion of the left nipple with serosanguineous discharge. The skin biopsy revealed proliferation of tubular structures, which corresponded to EAN. She was treated with 4 sessions of cryosurgery (open cryospray with liquid nitrogen) over 6 months, and the skin lesion resolved completely without any recurrence for 12 months. Although further study is required to determine the optimal treatment regimen for EAN, cryosurgery should be considered as an effective option to surgical excision.

Indexed as

Apocrine glandsCryosurgeryErosive adenomatosis of the nipple

Identifiers

PMID33935461
PMCPMC8081994
OpenAlexW3139284977

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.