Evidence map›Paper›PMID 33934622›Full record

ArticleHypertension (Dallas, Tex. : 1979)2021

Mineralocorticoid and Estrogen Receptors in Endothelial Cells Coordinately Regulate Microvascular Function in Obese Female Mice.

Lauren A Biwer, Brigett V Carvajal, Qing Lu, Joshua J Man, Iris Z Jaffe

Open access · bronzeAbstract read
In one paragraph

Article in Hypertension (Dallas, Tex. : 1979), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Lauren A BiwerMolecular Cardiology Research Institute, Tufts Medical Center, Boston, MA (L.A.B., B.V.C., Q.L., J.J.M., I.Z.J.).
Brigett V CarvajalMolecular Cardiology Research Institute, Tufts Medical Center, Boston, MA (L.A.B., B.V.C., Q.L., J.J.M., I.Z.J.).
Qing LuMolecular Cardiology Research Institute, Tufts Medical Center, Boston, MA (L.A.B., B.V.C., Q.L., J.J.M., I.Z.J.).
Joshua J ManMolecular Cardiology Research Institute, Tufts Medical Center, Boston, MA (L.A.B., B.V.C., Q.L., J.J.M., I.Z.J.).
Iris Z JaffeMolecular Cardiology Research Institute, Tufts Medical Center, Boston, MA (L.A.B., B.V.C., Q.L., J.J.M., I.Z.J.).
Tufts University · USTufts Medical Center · US

Funding

TRAINING PROGRAM IN HYPERTENSIONT32HL007609 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI ADLER, GAIL KURR · 1985 to 2022
$10.2M
The Role of Vascular MR-Regulated Genes in Vascular Function and DiseaseR01HL095590 · NHLBI · TUFTS MEDICAL CENTER · PI Iris Z Jaffe · 2009 to 2026
$7.7M
Tufts Post-Baccalaureate Research Education ProgramR25GM066567 · NIGMS · TUFTS UNIVERSITY BOSTON · PI RIOS, MARIBEL · 2002 to 2024
$5.7M
Role of the myeloid mineralocorticoid receptor in vascular inflammation in atherosclerosisF30HL152505 · NHLBI · TUFTS UNIVERSITY BOSTON · PI MAN, JOSHUA JAMES · 2020 to 2022
$144k
NHLBI NIH HHS F30 HL152505NHLBI NIH HHS R01 HL095590NHLBI NIH HHS T32 HL007609NIGMS NIH HHS R25 GM066567
6 · The paper itself

Abstract

[Figure: see text].

Indexed as

AnimalsEndothelium, VascularEstrogen Receptor AntagonistsEstrogensFemaleFulvestrantMiceMice, KnockoutMice, ObeseMicrovesselsNitric Oxide Synthase Type IIIObesityPhosphorylationReceptors, EstrogenReceptors, MineralocorticoidSignal TransductionEstrogen Receptor AntagonistsEstrogensFulvestrantNitric Oxide Synthase Type IIIReceptors, EstrogenReceptors, Mineralocorticoidendotheliumestrogen receptormineralocorticoid receptorobesityvasodilation

Identifiers

PMID33934622
PMCPMC8119365
OpenAlexW3158621598

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.